Gene · 10347
ABCA7: ATP binding cassette subfamily A member 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCA7: ATP binding cassette subfamily A member 7. Genes, record 10347. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10347
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IZY2 | Phospholipid-transporting ATPase ABCA7 | 2,146 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38373 | Q8IZY2 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38374 | Q8IZY2 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 257 | Q8IZY2 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1735 | Q8IZY2 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 106 | Q8IZY2 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 184 | Q8IZY2 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 184 | Q8IZY2 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 257 | Q8IZY2 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1735 | Q8IZY2 | Espacenet |
| JP 2025062601 A | 2025-04-14 | 10 | Q8IZY2 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,577
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCA7 papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 99 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 29 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 24 | 2025 |
| U24AG056270 | National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS) | 24 | 2025 |
| U24AG041689 | THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE | 19 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 15 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 14 | 2025 |
| U54AG052427 | Genome Center for Alzheimer's Disease (GCAD) | 13 | 2025 |
| P30AG066509 | University of Washington Alzheimer's Disease Research Center | 11 | 2025 |
| P30AG062422 | New Approaches to Dementia Heterogeneity | 9 | 2025 |
1 to 10 of 1,577Source NIH's project files
See all 1,577 nih grantsPapers1,658
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular and genetic basis of alzheimer's disease and emerging treatment Modalities. | Neurodegener Dis Manag | 2026 | 42825454 | PubTator, text mining | PubMed |
| Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk. | Am J Hum Genet | 2026 | 42648288 | PubTator, text mining | PubMed |
| Descriptive Analysis of Genetic Variants in Individuals Without a Clinical Diagnosis of Alzheimer's Disease in a Population from Southwestern Colombia. | Curr Alzheimer Res | 2026 | 42634522 | PubTator, text mining | PubMed |
| ABCA7-80 moderates vascular stiffness-p-tau217 association in older African Americans. | Alzheimers Dement (N Y) | 2026 | 42582950 | PubTator, text mining | PubMed |
| Disease-predominant loci across Alzheimer's disease, Parkinson's disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization. | Front Genet | 2026 | 42460153 | PubTator, text mining | PubMed |
| ABCA7 Mutation in Behavioral Variant of Frontotemporal Dementia: A Case Report. | Case Rep Neurol | 2026 | 42422539 | PubTator, text mining | PubMed |
| Genetic and structural characterisation of alzheimer's disease associated variants in an Eastern Indian cohort. | Metab Brain Dis | 2026 | 42412289 | PubTator, text mining | PubMed |
| CHCHD10 Mitigates Alzheimer's Disease-Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons. | Adv Sci (Weinh) | 2026 | 42348392 | PubTator, text mining | PubMed |
| GWAS on short tandem repeats identifies genetic mechanisms in Alzheimer's disease. | Nat Commun | 2026 | 42243151 | PubTator, text mining | PubMed |
| PathoAnalyzer-I: An Integrative Bioinformatics Platform for Chronic Disease Analysis. | Bioinform Biol Insights | 2026 | 42137421 | PubTator, text mining | PubMed |
1 to 10 of 1,658
See all 1,658 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10347
GET https://conductscience.org/api/genes/v1/10347/patents?page=2