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Gene · 10347

ABCA7: ATP binding cassette subfamily A member 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCA7: ATP binding cassette subfamily A member 7. Genes, record 10347. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10347

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Gene

Symbol
ABCA7
HGNC
Name
ATP binding cassette subfamily A member 7
HGNC
NCBI Gene ID
10347
NCBI Gene
HGNC ID
HGNC:37
HGNC
Ensembl
ENSG00000064687
NCBI Gene
Aliases
ABCA-SSN, ABCX, AD9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IZY2Phospholipid-transporting ATPase ABCA72,1466Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438373Q8IZY2Espacenet
JP 2026004568 A2026-01-1438374Q8IZY2Espacenet
EP 4640849 A22025-10-29257Q8IZY2Espacenet
EP 4641201 A22025-10-291735Q8IZY2Espacenet
EP 4641202 A22025-10-29106Q8IZY2Espacenet
JP 2025529142 A2025-09-04184Q8IZY2Espacenet
US 12371689 B22025-07-29184Q8IZY2Espacenet
JP 2025519096 A2025-06-24257Q8IZY2Espacenet
JP 2025517969 A2025-06-121735Q8IZY2Espacenet
JP 2025062601 A2025-04-1410Q8IZY2Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,577

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCA7 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)992025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study292025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions242025
U24AG056270National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)242025
U24AG041689THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE192025
U19AG024904Alzheimer's Disease Neuroimaging Initiative (ADNI4)152025
R01NS017950Precursors of Stroke Incidence and Prognosis142025
U54AG052427Genome Center for Alzheimer's Disease (GCAD)132025
P30AG066509University of Washington Alzheimer's Disease Research Center112025
P30AG062422New Approaches to Dementia Heterogeneity92025

1 to 10 of 1,577Source NIH's project files

See all 1,577 nih grants

Papers1,658

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular and genetic basis of alzheimer's disease and emerging treatment Modalities.Neurodegener Dis Manag202642825454PubTator, text miningPubMed
Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk.Am J Hum Genet202642648288PubTator, text miningPubMed
Descriptive Analysis of Genetic Variants in Individuals Without a Clinical Diagnosis of Alzheimer's Disease in a Population from Southwestern Colombia.Curr Alzheimer Res202642634522PubTator, text miningPubMed
ABCA7-80 moderates vascular stiffness-p-tau217 association in older African Americans.Alzheimers Dement (N Y)202642582950PubTator, text miningPubMed
Disease-predominant loci across Alzheimer's disease, Parkinson's disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization.Front Genet202642460153PubTator, text miningPubMed
ABCA7 Mutation in Behavioral Variant of Frontotemporal Dementia: A Case Report.Case Rep Neurol202642422539PubTator, text miningPubMed
Genetic and structural characterisation of alzheimer's disease associated variants in an Eastern Indian cohort.Metab Brain Dis202642412289PubTator, text miningPubMed
CHCHD10 Mitigates Alzheimer's Disease-Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons.Adv Sci (Weinh)202642348392PubTator, text miningPubMed
GWAS on short tandem repeats identifies genetic mechanisms in Alzheimer's disease.Nat Commun202642243151PubTator, text miningPubMed
PathoAnalyzer-I: An Integrative Bioinformatics Platform for Chronic Disease Analysis.Bioinform Biol Insights202642137421PubTator, text miningPubMed

1 to 10 of 1,658

See all 1,658 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10347

GET https://conductscience.org/api/genes/v1/10347/patents?page=2