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Gene · 10371

SEMA3A: semaphorin 3A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SEMA3A: semaphorin 3A. Genes, record 10371. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10371

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Gene

Symbol
SEMA3A
HGNC
Name
semaphorin 3A
HGNC
NCBI Gene ID
10371
NCBI Gene
HGNC ID
HGNC:10723
HGNC
Ensembl
ENSG00000075213
NCBI Gene
Aliases
COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14563Semaphorin-3A7710Ensembl, GeneID, HGNC

Source UniProt

Patents117

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192472Q14563Espacenet
WO 2025234433 A2025-11-133Q14563Espacenet
EP 4641201 A22025-10-292057Q14563Espacenet
JP 2025147176 A2025-10-0611865Q14563Espacenet
JP 2025147176 A2025-10-0611866Q14563Espacenet
JP 2025138725 A2025-09-251936Q14563Espacenet
JP 2025138725 A2025-09-252975Q14563Espacenet
JP 2025529142 A2025-09-047657Q14563Espacenet
US 12371689 B22025-07-297657Q14563Espacenet
JP 2025517969 A2025-06-122057Q14563Espacenet

1 to 10 of 117

See all 117 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,769

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSEMA3A papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
P30CA006973Regional Oncology Research Center42025
P30CA016087Cancer Center Support Grant42025
P30EY001792P30 Core Grant for Vision Research42025
P20GM103449Vermont Biomedical Research Network-Vermont INBRE32025
P30CA008748Cancer Center Support Grant32025
P30CA013330Cancer Center Support Grant32025
P30CA091842Cancer Center Support Grant32025
P30DK063491Diabetes Research Center (DRC)32025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)32025

1 to 10 of 1,769Source NIH's project files

See all 1,769 nih grants

Papers3,028

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Corrigendum to "Decreased expression of Sema3A, an immune modulator, in blood sample of multiple sclerosis patients" [Gene 610 (2017) 59-63].Gene202642763226PubTator, text miningPubMed
SGLT2 Inhibitors Are Associated With Suppression of the Sema3A/NRP1/Plexin-A1 Signaling Axis in Postmenopausal Women With Type 2 Diabetes: Evidence From Propensity Score-Matched Analysis.J Diabetes202642649130PubTator, text miningPubMed
Targeting Semaphorin-plexin Signaling in Glioblastoma: Implications for Tumor Invasion, Angiogenesis, and Treatment Resistance.Curr Neurovasc Res202642634324PubTator, text miningPubMed
Advances in the study of the role of bone immunity in physiological and pathological processes related to bone metabolism.Int Immunopharmacol202642546515PubTator, text miningPubMed
Differences in immune-related semaphorin levels in the CSF and serum of newly diagnosed, treatment-naive patients with relapsing-remitting multiple sclerosis: a case-control study.Front Neurol202642524290PubTator, text miningPubMed
Evaluation of serum semaphorin-3A and interleukin 6 levels in patients with neovascular age-related macular degeneration.BMC Ophthalmol202642449255PubTator, text miningPubMed
The Role of Sensory and Sympathetic Nerves in the Development and Bone Metabolism of Mandible.Oral Dis202642438044PubTator, text miningPubMed
Semaphorin 3A promotes resilience of sleep and cognition to brain injury.bioRxiv202642427776PubTator, text miningPubMed
Combined HS6ST1 and HS6ST2 loss disrupts the formation and migration of gonadotropin-releasing hormone neurons.Development202642358159PubTator, text miningPubMed
Diverse Roles of Semaphorins on T Cell Activation, Differentiation, Migration, and Effector Functions.Cells202642346074PubTator, text miningPubMed

1 to 10 of 3,028

See all 3,028 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10371

GET https://conductscience.org/api/genes/v1/10371/patents?page=2