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TUBA1B: tubulin alpha 1b

1 protein, 80 patents, 90 drugs, 8,728 trials, 13,950 NIH grants and 26,622 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTUBA1BHGNC
Nametubulin alpha 1bHGNC
NCBI Gene ID10376NCBI Gene
HGNC IDHGNC:18809HGNC
EnsemblENSG00000123416NCBI Gene
AliasesK-ALPHA-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P68363Tubulin alpha-1B chain45140Ensembl, GeneID, HGNCUniProt

Patents 80

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-2447P68363Espacenet
US 12560619 B22026-02-2448P68363Espacenet
EP 4650780 A22025-11-196225P68363Espacenet
EP 4641202 A22025-10-295089P68363Espacenet
JP 2025517970 A2025-06-126225P68363Espacenet
KR 1020250017231 A2025-02-045089P68363Espacenet
EP 4438620 A12024-10-0257P68363Espacenet
EP 4438622 A12024-10-0257P68363Espacenet
US 12038446 B22024-07-1647P68363Espacenet
US 12038446 B22024-07-1648P68363Espacenet

Drugs 90

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL
BIIB-015CHEMBL2109575Tubulin inhibitorINHIBITORChEMBL

Trials 8728

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

NIH grants 13950

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1522,025NIH's project files
P30CA008748Cancer Center Support Grant982,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant772,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support542,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center352,025NIH's project files
P30CA016058Cancer Center Support Grant342,025NIH's project files
P30CA016087Cancer Center Support Grant342,025NIH's project files
P30CA047904Cancer Center Support Grant332,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA322,025NIH's project files
P30CA016086Cancer Center Support Grant312,025NIH's project files

Papers 26622

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825379PubTator, text miningPubMed
42798205PubTator, text miningPubMed
42773388PubTator, text miningPubMed
42764120PubTator, text miningPubMed
42759651PubTator, text miningPubMed
42758788PubTator, text miningPubMed
42727187PubTator, text miningPubMed
42719948PubTator, text miningPubMed
42715866PubTator, text miningPubMed
42702897PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license