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Gene · 10381

TUBB3: tubulin beta 3 class III

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. TUBB3: tubulin beta 3 class III. Genes, record 10381. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/10381

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
TUBB3
HGNC
Name
tubulin beta 3 class III
HGNC
NCBI Gene ID
10381
NCBI Gene
HGNC ID
HGNC:20772
HGNC
Ensembl
ENSG00000258947
NCBI Gene
Aliases
CDCBM, CDCBM1, CFEOM3, CFEOM3A, CFEOM3A1, FEOM3, TUBB4, beta-4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13509Tubulin beta-3 chain45029Ensembl, GeneID, HGNC

Source UniProt

Patents79

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468526Q13509Espacenet
EP 4650780 A22025-11-195303Q13509Espacenet
EP 4641201 A22025-10-294890Q13509Espacenet
EP 4641202 A22025-10-294938Q13509Espacenet
JP 2025529142 A2025-09-043773Q13509Espacenet
US 12371689 B22025-07-293773Q13509Espacenet
JP 2025517969 A2025-06-124890Q13509Espacenet
JP 2025517970 A2025-06-125303Q13509Espacenet
KR 1020250017231 A2025-02-044938Q13509Espacenet
US 11976296 B22024-05-076Q13509Espacenet

1 to 10 of 79

See all 79 patents

Drugs91

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABT-751CHEMBL20684Tubulin beta inhibitorINHIBITORChEMBL
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 91

See all 91 drugs

Trials8,740

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,740

See all 8,740 trials

NIH grants2,833

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant122025
P30CA008748Cancer Center Support Grant102025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders102025
P30CA046934University of Colorado Cancer Center Support Grant92025
P30CA036727Buffett Cancer Center Support Grant62025
T32EY007143Visual Science Training Program62025
P30CA006973Regional Oncology Research Center52025
P30CA014195Cancer Center Support Grant (CCSG)52025
P30CA033572Cancer Center Support Grant52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant52025

1 to 10 of 2,833Source NIH's project files

See all 2,833 nih grants

Papers4,386

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42771513PubTator, text miningPubMed
42748994PubTator, text miningPubMed
42704317PubTator, text miningPubMed
42689320PubTator, text miningPubMed
42675957PubTator, text miningPubMed
42596828PubTator, text miningPubMed
42593952PubTator, text miningPubMed
42582771PubTator, text miningPubMed
42570282PubTator, text miningPubMed
42508561PubTator, text miningPubMed

1 to 10 of 4,386

See all 4,386 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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