Gene · 10392
NOD1: nucleotide binding oligomerization domain containing 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NOD1: nucleotide binding oligomerization domain containing 1. Genes, record 10392. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10392
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | 953 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents50
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 405 | Q9Y239 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 405 | Q9Y239 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 7471 | Q9Y239 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 59035 | Q9Y239 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 162006 | Q9Y239 | Espacenet |
| KR 1020210107561 A | 2021-09-01 | 4 | Q9Y239 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 7566 | Q9Y239 | Espacenet |
| US 10918740 B2 | 2021-02-16 | 9151 | Q9Y239 | Espacenet |
| US 10869935 B2 | 2020-12-22 | 9151 | Q9Y239 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 7471 | Q9Y239 | Espacenet |
1 to 10 of 50
See all 50 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,796
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NOD1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA116087 | H. pylori-induced Inflammation and Gastric Cancer | 21 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 19 | 2025 |
| R01CA077955 | H. Pylori Relationship to Digestive Diseases and Cancer | 17 | 2025 |
| ZIAAI000354 | Immunoregulatory Defects In Inflammatory Bowel Disease | 9 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 8 | 2025 |
| P30DK034989 | Yale Liver Center | 7 | 2025 |
| R37AI101935 | Inflammatory Caspases in Innate Immunity and Inflammation | 7 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| ZIAAI000432 | Regulation Of Immune Responses In Humans and in Experimental Animals | 6 | 2025 |
| R01AI124346 | Innate immune signaling and stress response | 5 | 2025 |
1 to 10 of 1,796Source NIH's project files
See all 1,796 nih grantsPapers3,459
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Primary human dermal fibroblasts selectively sense LPS, poly I:C and ADP heptose and initiate immune response mostly through chemokine secretion. | Innate Immun | 2026 | 42751893 | PubTator, text mining | PubMed |
| Whole-Exome Sequencing Identifies Candidate Genomic Features Associated with Response to Platinum-Based Chemotherapy and Ixabepilone-Based Treatment in Ovarian Cancer. | Int J Mol Sci | 2026 | 42737428 | PubTator, text mining | PubMed |
| Expression, Regulation and Therapeutic Implications of Nod-Like Receptors in Endodontics: A Narrative Review. | Int Endod J | 2026 | 42677679 | PubTator, text mining | PubMed |
| Conjugated NOD1-Centered Dual Agonists Exhibit Modest In Vitro Immunomodulation but Potent In Vivo Adjuvanticity. | ACS Bio Med Chem Au | 2026 | 42630639 | PubTator, text mining | PubMed |
| Immunomodulatory effect of Lacticaseibacillus rhamnosus and Lactobacillus acidophilus in human dendritic cells. | Arch Microbiol | 2026 | 42573797 | PubTator, text mining | PubMed |
| Immunogenicity of a Candidate Hepatitis C Vaccine Based on Non-Structural DNA-Protein Sequences and a Novel Complex Adjuvant. | Vaccines (Basel) | 2026 | 42506677 | PubTator, text mining | PubMed |
| Integrative multi-omics and mendelian randomization reveal the critical role of pyroptosis in prognosis and therapy of lung squamous cell carcinomas. | Front Cell Dev Biol | 2026 | 42488553 | PubTator, text mining | PubMed |
| CSN3 promotes gastric cancer progression and is associated with immune infiltration and inflammatory signaling. | Transl Cancer Res | 2026 | 42445438 | PubTator, text mining | PubMed |
| NOD1 is a key mediator of atrial myopathy in heart failure. | Theranostics | 2026 | 42370189 | PubTator, text mining | PubMed |
| AKT-mediated phosphorylation of ZDHHC5 promotes NOD1 palmitoylation and innate immune signaling. | Front Immunol | 2026 | 42344932 | PubTator, text mining | PubMed |
1 to 10 of 3,459
See all 3,459 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10392
GET https://conductscience.org/api/genes/v1/10392/patents?page=2