Gene · 10397
NDRG1: N-myc downstream regulated 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NDRG1: N-myc downstream regulated 1. Genes, record 10397. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10397
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q92597 | Protein NDRG1 | 394 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents52
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55846 | Q92597 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55848 | Q92597 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5283 | Q92597 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4869 | Q92597 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4869 | Q92597 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5283 | Q92597 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32104 | Q92597 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32106 | Q92597 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32104 | Q92597 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32106 | Q92597 | Espacenet |
1 to 10 of 52
See all 52 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,937
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NDRG1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 31 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| P50CA101942 | DF/HCC Kidney Cancer SPORE (supplement) | 6 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| U01CA113913 | Prostate Cancer Biomarker and Imaging Validation Alliance: Emory University, University of Alabama Birmingham, and University of Texas Southwestern | 5 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 4 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 4 | 2025 |
1 to 10 of 1,937Source NIH's project files
See all 1,937 nih grantsPapers3,293
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The GSEC-encoded polypeptide GESP drives colorectal cancer tumorigenesis via NPM1-c-Myc-mediated repression of NDRG1. | Oncogene | 2026 | 42680813 | PubTator, text mining | PubMed |
| NDRG1 expression in cancers confers dependence on DNA damage repair and sensitivity to quinacrine. | Sci Signal | 2026 | 42479816 | PubTator, text mining | PubMed |
| Spatial and single-cell profiling identify NDRG1⁺ macrophages as key hallmark of angiogenic remodeling and platinum resistance in HGSOC. | Transl Oncol | 2026 | 42442223 | PubTator, text mining | PubMed |
| Machine Learning-Based Identification of Tamoxifen Resistance-Associated Genes and Their Application in Prognostic Modeling of Breast Cancer. | J Vis Exp | 2026 | 42441516 | PubTator, text mining | PubMed |
| Single-cell and bulk transcriptomics identify senescence-related EMT transcriptional programs and a prognostic framework in pancreatic ductal adenocarcinoma. | BMC Gastroenterol | 2026 | 42420840 | PubTator, text mining | PubMed |
| ANGPTL4 contributes to osimertinib resistance through NDRG1-associated extracellular matrix remodeling in EGFR-mutant NSCLC organoid models. | Cancer Cell Int | 2026 | 42415069 | PubTator, text mining | PubMed |
| RIN4 fragments released by AvrRpt2 promote NDR1-dependent activation of RPS2. | Plant Cell | 2026 | 42413037 | PubTator, text mining | PubMed |
| Silencing the Signal: The Metastasis Suppressor NDRG1 Disrupts Small Extracellular Vesicle-Mediated Crosstalk in Pancreatic Cancer. | J Extracell Vesicles | 2026 | 42377994 | PubTator, text mining | PubMed |
| Application of single-cell RNA sequencing in preeclampsia. | Front Glob Womens Health | 2026 | 42367612 | PubTator, text mining | PubMed |
| Multiomics Reveals NDRG1-Driven Oral Squamous Cell Carcinoma Progression: Competitive Endogenous RNAs Regulation and Proangiogenic Microenvironment Remodelling. | Int Dent J | 2026 | 42364411 | PubTator, text mining | PubMed |
1 to 10 of 3,293
See all 3,293 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10397
GET https://conductscience.org/api/genes/v1/10397/patents?page=2