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Gene · 10399

RACK1: receptor for activated C kinase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RACK1: receptor for activated C kinase 1. Genes, record 10399. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10399

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Gene

Symbol
RACK1
HGNC
Name
receptor for activated C kinase 1
HGNC
NCBI Gene ID
10399
NCBI Gene
HGNC ID
HGNC:4399
HGNC
Ensembl
ENSG00000204628
NCBI Gene
Aliases
GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P63244Small ribosomal subunit protein RACK1317191Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12545636 B22026-02-1034P63244Espacenet
EP 4650780 A22025-11-1914987P63244Espacenet
EP 4641202 A22025-10-297343P63244Espacenet
JP 2025517970 A2025-06-1214987P63244Espacenet
KR 1020250017231 A2025-02-047343P63244Espacenet
US 12215068 B22025-02-0434P63244Espacenet
JP 2024534697 A2024-09-2034P63244Espacenet
JP 2024533865 A2024-09-1234P63244Espacenet
US 11773061 B22023-10-0334P63244Espacenet
US 11446398 B22022-09-2036842P63244Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,893

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRACK1 papersNewest fiscal year
R01AI127456Poxvirus manipulation of the host cell protein synthesis machinery112025
P30CA013148Comprehensive Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant62025
ZIAHD000412Molecular Regulation Of RNA Metabolism52025
P30CA008748Cancer Center Support Grant42025
P30EY011373CWRU NEI Vision Center Core Grant42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA006973Regional Oncology Research Center32025
P30CA016086Cancer Center Support Grant32025
P30CA016087Cancer Center Support Grant32025

1 to 10 of 1,893Source NIH's project files

See all 1,893 nih grants

Papers3,110

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Differential analysis of urinary stable downregulated proteins in male patients after colorectal cancer surgery.Front Oncol202642707234PubTator, text miningPubMed
Whole-transcriptome sequencing analysis to identify key non-coding RNAs in the pathogenesis of pulmonary tuberculosis.Public Health Action202642639598PubTator, text miningPubMed
Exploring the Association Between Rheumatoid Arthritis and Parkinson's Disease: Evidence from 2001-2016 NHANES, Real-World Clinical Data and Bioinformatics Analysis.J Inflamm Res202642572743PubTator, text miningPubMed
Targeting GEM Reprograms Macrophages and Overcomes Immunotherapy Resistance in Esophageal Squamous Cell Carcinoma.Cancer Res202642561099PubTator, text miningPubMed
RACK1 in host immune response to infections: molecular mechanisms and therapeutic potentials.Front Immunol202642421949PubTator, text miningPubMed
SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling.Cancer Res202642406998PubTator, text miningPubMed
Correction: Molecular mechanisms of RACK1-driven metastasis in pancreatic ductal adenocarcinoma revealed by single-cell RNA sequencing.Discov Oncol202642360598PubTator, text miningPubMed
PKCβII Activation Promotes Membrane-Proximal Enrichment of Ribosome-Bound RACK1.Int J Mol Sci202642353031PubTator, text miningPubMed
Systems biology and single-cell transcriptome analysis identify potential therapeutic targets and impaired neurogenesis in human cortical development related to autism spectrum disorder.Mol Divers202642319587PubTator, text miningPubMed
RACK1 governs a dual metabolic switch in lung adenocarcinoma through c-Src/G6PD and TRIM21/LDHA Axes.Cell Death Dis202642215440PubTator, text miningPubMed

1 to 10 of 3,110

See all 3,110 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10399

GET https://conductscience.org/api/genes/v1/10399/patents?page=2