ConductScience.org, home

Gene · 10400

PEMT: phosphatidylethanolamine N-methyltransferase

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PEMT: phosphatidylethanolamine N-methyltransferase. Genes, record 10400. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10400

On this page

Gene

Symbol
PEMT
HGNC
Name
phosphatidylethanolamine N-methyltransferase
HGNC
NCBI Gene ID
10400
NCBI Gene
HGNC ID
HGNC:8830
HGNC
Ensembl
ENSG00000133027
NCBI Gene
Aliases
PEAMT, PEMPT, PEMT2, PLMT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UBM1Phosphatidylethanolamine N-methyltransferase1990Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1911316Q9UBM1Espacenet
JP 2025529142 A2025-09-043437Q9UBM1Espacenet
US 12371689 B22025-07-293437Q9UBM1Espacenet
JP 2025517970 A2025-06-1211316Q9UBM1Espacenet
US 11446398 B22022-09-2062499Q9UBM1Espacenet
US 11446398 B22022-09-2062500Q9UBM1Espacenet
US 11408034 B22022-08-09530Q9UBM1Espacenet
US 11408034 B22022-08-09532Q9UBM1Espacenet
US 11400116 B22022-08-023641Q9UBM1Espacenet
US 11400116 B22022-08-026002Q9UBM1Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,080

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePEMT papersNewest fiscal year
P30DK056350Nutrition Obesity Research Center (NORC)452025
P30ES010126UNC Center for Environmental Health and Susceptibility242025
P30ES009089Center for Environmental Health in Northern Manhattan82025
P30DK020572Michigan Diabetes Research Center (MDRC)42025
P30DK034987Center for Gastrointestinal Biology and Disease42025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)42025
T32HD087137TRAINING IN MATERNAL AND CHILD NUTRITION42025
ZIAHG000167The contribution folate and vitamin B12 genes to disease.42025
K12HD001271Colorado Women's Reproductive Health Research Career Development Center32025
P30CA008748Cancer Center Support Grant32025

1 to 10 of 1,080Source NIH's project files

See all 1,080 nih grants

Papers1,401

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Stroma-Dominant Colorectal Cancer Harbors CAF-Rich Spatial Architecture and EMT-Associated Cancer Cell Plasticity Detectable After Dissemination.Biomolecules202642793094PubTator, text miningPubMed
Are sustainable plant-based diets suitable for all? A nutrigenetic perspective.Nutr Health202642593171PubTator, text miningPubMed
A prognostic signature based on methionine metabolism-related genes for cervical cancer: integrated transcriptomic and experimental validation.PeerJ202642500207PubTator, text miningPubMed
Development and Validation of a Crotonylation-Related Prognostic Risk Model for Cholangiocarcinoma Based on Integrative Transcriptome Analysis.Dig Dis Sci202642400718PubTator, text miningPubMed
Endocrine therapy-specific lineage and partial epithelial-mesenchymal reprogramming defines divergent resistant cell-states in ER+ breast cancer.bioRxiv202642182314PubTator, text miningPubMed
Lipid metabolism links seminal PFAS exposure to IVF outcomes.Environ Int202642119252PubTator, text miningPubMed
Regulation of Intracellular Lipid Droplets by Tea: Mechanistic Insights and Food Applications.Compr Rev Food Sci Food Saf202641940732PubTator, text miningPubMed
Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer's Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations.FASEB J202641930605PubTator, text miningPubMed
A 'Standard of Care PLUS' Model for Preterm Birth Prevention: Integrating Nutrient and Gene Variant Analysis with Targeted Interventions.J Pers Med202641893003PubTator, text miningPubMed
Urinary extracellular vesicle metabolomic profiling reveals a distinct molecular signature for the non-invasive diagnosis of lupus nephritis.Front Immunol202641782855PubTator, text miningPubMed

1 to 10 of 1,401

See all 1,401 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10400

GET https://conductscience.org/api/genes/v1/10400/patents?page=2