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Gene · 10410

IFITM3: interferon induced transmembrane protein 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IFITM3: interferon induced transmembrane protein 3. Genes, record 10410. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10410

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Gene

Symbol
IFITM3
HGNC
Name
interferon induced transmembrane protein 3
HGNC
NCBI Gene ID
10410
NCBI Gene
HGNC ID
HGNC:5414
HGNC
Ensembl
ENSG00000142089
NCBI Gene
Aliases
1-8U, DSPA2b, IP15
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01628Interferon-induced transmembrane protein 31330Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450053Q01628Espacenet
EP 4650780 A22025-11-1911686Q01628Espacenet
JP 2025529142 A2025-09-042040Q01628Espacenet
US 12371689 B22025-07-292040Q01628Espacenet
JP 2025517970 A2025-06-1211686Q01628Espacenet
JP 2023545539 A2023-10-3011Q01628Espacenet
KR 1020230084512 A2023-06-136Q01628Espacenet
US 11446398 B22022-09-2041037Q01628Espacenet
JP 2022524081 A2022-04-27144008Q01628Espacenet
US 11142794 B22021-10-1246Q01628Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,372

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIFITM3 papersNewest fiscal year
R01AI130110Mechanisms of innate resistance to virus infections222025
P30CA008748Cancer Center Support Grant142025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital92025
ZIABC011779Mechanisms of Virus Entry into Cells and Antiviral Barriers Limiting Entry92025
UL1TR001863Yale Clinical and Translational Science Award82025
P51OD011132Emory National Primate Research Center72025
P30CA016672Cancer Center Support Grant62025
P30AG066519The Alzheimer's Disease Research Center at the University of California, Irvine52025
P30CA016058Cancer Center Support Grant52025
P30CA042014Cancer Center Support Grant52025

1 to 10 of 2,372Source NIH's project files

See all 2,372 nih grants

Papers3,083

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated Single-Cell and Machine-Learning Analysis Identifies Antigen-Presenting Macrophage-Associated Genes in Pediatric Community-Acquired Pneumonia.Curr Med Chem202642816984PubTator, text miningPubMed
PRELP-associated transcriptomic remodeling links alternative splicing and immune checkpoint blockade outcome in melanoma.Front Immunol202642813001PubTator, text miningPubMed
Functional redundancy, complementation, and cross-talk between CH25h and IFITM3 in infection and in IFITM3 trafficking and secretion.J Virol202642803587PubTator, text miningPubMed
eNAMPT-IFITM3 axis links neuroinflammation to γ-secretase activation.iScience202642765029PubTator, text miningPubMed
Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes.J Clin Invest202642741944PubTator, text miningPubMed
IFITM3 at the viral fusion-pore checkpoint: membrane energetics and entry-route-dependent outcomes.Front Immunol202642707764PubTator, text miningPubMed
IFITM3 Is Elevated in BAL and Plasma Following Infection in ICU Setting.FASEB J202642664046PubTator, text miningPubMed
Integrated Functional Characterization of a Panel of Clinical Orthoflavivirus Isolates Reveals Distinct Replication and Innate Immune Response Profiles in Human Keratinocytes.Viruses202642655646PubTator, text miningPubMed
Interferon-induced transmembrane (IFITM) proteins at the tumour-immune interface: A four-axis framework for their context-dependent roles.Clin Transl Med202642613969PubTator, text miningPubMed
Targeted nanoparticle-mediated Co-delivery of IFITM3 KO and ponatinib reverses TKI resistance in chronic myeloid leukemia.Front Pharmacol202642582078PubTator, text miningPubMed

1 to 10 of 3,083

See all 3,083 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10410

GET https://conductscience.org/api/genes/v1/10410/patents?page=2