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YAP1: Yes1 associated transcriptional regulator

1 protein, 35 patents, 0 drugs, 0 trials, 8,491 NIH grants and 25,010 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolYAP1HGNC
NameYes1 associated transcriptional regulatorHGNC
NCBI Gene ID10413NCBI Gene
HGNC IDHGNC:16262HGNC
EnsemblENSG00000137693NCBI Gene
AliasesCOB1, YAP, YAP-1, YAP2, YAP65, YKINCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P46937Transcriptional coactivator YAP150441Ensembl, GeneID, HGNCUniProt

Patents 35

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4724572 A12026-04-151P46937Espacenet
EP 4650780 A22025-11-193161P46937Espacenet
EP 4641201 A22025-10-292725P46937Espacenet
JP 2025517969 A2025-06-122725P46937Espacenet
JP 2025517970 A2025-06-123161P46937Espacenet
EP 4565705 A22025-06-114P46937Espacenet
US 12324818 B22025-06-101P46937Espacenet
JP 2024123008 A2024-09-109153P46937Espacenet
US 11860162 B22024-01-021165P46937Espacenet
US 11672795 B22023-06-132P46937Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8491

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1812,025NIH's project files
P30CA008748Cancer Center Support Grant1742,025NIH's project files
P30DK026743UCSF Liver Center312,025NIH's project files
R01EY015708Control of Cell Number in Developing Retina312,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant292,025NIH's project files
U24CA213274Coordinating center for the NCI small cell lung cancer research consortium272,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant262,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology232,025NIH's project files
P50CA217694SPORE in Soft Tissue Sarcoma222,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant212,025NIH's project files

Papers 25010

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823957PubTator, text miningPubMed
42818273PubTator, text miningPubMed
42816036PubTator, text miningPubMed
42814390PubTator, text miningPubMed
42813612PubTator, text miningPubMed
42811281PubTator, text miningPubMed
42810779PubTator, text miningPubMed
42810594PubTator, text miningPubMed
42806999PubTator, text miningPubMed
42804919PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license