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PRMT5: protein arginine methyltransferase 5
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Gene · 10419

Papers3,714

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

161 to 180 of 3,714

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TitleJournalYearPMIDFound bySource
Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.Cell Death Dis202641629269PubTator, text miningPubMed
Posttranscriptional regulation of PD-1 by PRMT5/WDR77 complex shapes T cell effector function and antitumor immunity.J Clin Invest202641623183PubTator, text miningPubMed
The role of m6A RNA methyltransferase METTL3 in drug resistance mechanisms in acute myeloid leukemia.Blood Res202641615563PubTator, text miningPubMed
Separate transcription and splicing gene networks are linked and coordinated by the pRb-E2F pathway.Nucleic Acids Res202641614303PubTator, text miningPubMed
Glutamine transporter SLC1A5 inhibits autophagy-mediated CD276 degradation to promote esophageal cancer progression.Cancer Biol Ther202641606955PubTator, text miningPubMed
Targeting PRMT5 in Adult T-Cell Leukemia/Lymphoma: Opportunities and Challenges.Viruses202641600858PubTator, text miningPubMed
Transcriptome-wide analysis of Arabidopsis DICER-LIKE1 RNA substrates.Nucleic Acids Res202641569152PubTator, text miningPubMed
Identifying and capitalizing on unique molecular alterations of mucinous ovarian carcinoma for the development of novel therapeutic strategies.Gynecol Oncol Rep202641567617PubTator, text miningPubMed
Sequence-dependent splicing dysregulation drives therapy resistance in pediatric AML.Cell Rep Med202641564858PubTator, text miningPubMed
Targeting the UFL1-AKT cascade suppresses triple-negative breast cancer progression.Nat Commun202641559059PubTator, text miningPubMed
Proteasome Cap Targeting Chimeras for Ubiquitination-Independent Targeted Protein Degradation.Angew Chem Int Ed Engl202641556619PubTator, text miningPubMed
The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1.Oncogenesis202641554700PubTator, text miningPubMed
Methionine restriction for cancer therapy: From preclinical studies to clinical trials.Cancer Pathog Ther202641550357PubTator, text miningPubMed
Exploring structural diversity and dynamic stability of small-molecule PRMT5 inhibitors through machine learning-based QSAR and molecular modelling.Mol Divers202641533017PubTator, text miningPubMed
Oxidative nucleophilic addition of amide enolates to π-deficient aromatic and heteroaromatic ring systems.Org Biomol Chem202641532682PubTator, text miningPubMed
Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer.J Med Chem202641527338PubTator, text miningPubMed
PRMT5 upregulates KCNMB4 expression via histone methylation to promote paclitaxel resistance in advanced nasopharyngeal carcinoma.Cell Death Dis202641513606PubTator, text miningPubMed
MTAP Deletion in Oncogenesis: A Synthetic Lethality Scenario.Cancer Res202641512197PubTator, text miningPubMed
Phosphorylation of T425 and methylation of R426 synergistically regulate IBDV VP1 function and viral replication.Vet Microbiol202641506171PubTator, text miningPubMed
Targeting of CDK1 and PRMT5 as a potential therapeutic combination for non-small cell lung cancer.Histol Histopathol202641487038PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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