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Gene · 10460

TACC3: transforming acidic coiled-coil containing protein 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TACC3: transforming acidic coiled-coil containing protein 3. Genes, record 10460. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10460

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Gene

Symbol
TACC3
HGNC
Name
transforming acidic coiled-coil containing protein 3
HGNC
NCBI Gene ID
10460
NCBI Gene
HGNC ID
HGNC:11524
HGNC
Ensembl
ENSG00000013810
NCBI Gene
Aliases
ERIC-1, ERIC1, OZEMA27, Tacc4, maskin
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y6A5Transforming acidic coiled-coil-containing protein 38385Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467544Q9Y6A5Espacenet
EP 4641202 A22025-10-294994Q9Y6A5Espacenet
US 12274699 B22025-04-154Q9Y6A5Espacenet
KR 1020250017231 A2025-02-044994Q9Y6A5Espacenet
EP 4484957 A12025-01-0116Q9Y6A5Espacenet
US 12123005 B22024-10-2292Q9Y6A5Espacenet
US 12006503 B22024-06-1192Q9Y6A5Espacenet
US 11920138 B22024-03-0592Q9Y6A5Espacenet
EP 4276200 A22023-11-1592Q9Y6A5Espacenet
US 11771698 B22023-10-034Q9Y6A5Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants992

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTACC3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant382025
P30CA016672Cancer Center Support Grant282025
P30CA006927Comprehensive Cancer Center Program at Fox Chase62025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant52025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes42025
P30CA016058Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025

1 to 10 of 992Source NIH's project files

See all 992 nih grants

Papers1,759

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
FGFR2 fusion as the key to targeted therapy - a case report with a diagnostic turning point.Klin Onkol202642663156PubTator, text miningPubMed
Urinary proteomic signature of exercise intolerance in patients at risk of heart failure: evidence from the HOMAGE trial.EBioMedicine202642531722PubTator, text miningPubMed
TACC3, correlated with immune cell infiltrates, is a novel prognostic biomarker in BRCA.Medicine (Baltimore)202642499031PubTator, text miningPubMed
Cross-Tissue Transcriptome-Wide Association Study Prioritizes Candidate Genes and Compound-Associated Signatures for Osteoarthritis.Curr Pharm Des202642381324PubTator, text miningPubMed
Identification of a novel PANoptosis-associated prognostic signature and immune landscape analysis in neuroblastoma with experimental validation.Front Immunol202642273677PubTator, text miningPubMed
A Multi-omics Investigation Identifies TACC3 as a Driver of Immunosuppression in Intrahepatic Cholangiocarcinoma via Activation of the STAT3-PD-L1 Axis.J Clin Transl Hepatol202642181836PubTator, text miningPubMed
The scaffold protein PRR14L is linked to mitotic fidelity and sensitivity to MPS1 inhibition.Mol Biol Cell202642160513PubTator, text miningPubMed
Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression.Bladder Cancer202642124891PubTator, text miningPubMed
Nationwide genomic data analysis of central nervous system tumors in Japan based on C-CAT database.Int J Clin Oncol202642089945PubTator, text miningPubMed

1 to 10 of 1,759

See all 1,759 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10460

GET https://conductscience.org/api/genes/v1/10460/patents?page=2