Gene · 10460
TACC3: transforming acidic coiled-coil containing protein 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TACC3: transforming acidic coiled-coil containing protein 3. Genes, record 10460. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10460
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | 838 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67544 | Q9Y6A5 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4994 | Q9Y6A5 | Espacenet |
| US 12274699 B2 | 2025-04-15 | 4 | Q9Y6A5 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4994 | Q9Y6A5 | Espacenet |
| EP 4484957 A1 | 2025-01-01 | 16 | Q9Y6A5 | Espacenet |
| US 12123005 B2 | 2024-10-22 | 92 | Q9Y6A5 | Espacenet |
| US 12006503 B2 | 2024-06-11 | 92 | Q9Y6A5 | Espacenet |
| US 11920138 B2 | 2024-03-05 | 92 | Q9Y6A5 | Espacenet |
| EP 4276200 A2 | 2023-11-15 | 92 | Q9Y6A5 | Espacenet |
| US 11771698 B2 | 2023-10-03 | 4 | Q9Y6A5 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants992
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TACC3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 38 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 28 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 6 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 6 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 5 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 992Source NIH's project files
See all 992 nih grantsPapers1,759
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Divergent microtubule-organizing center strategies in mammalian gametogenesis. | Trends Open | 2026 | 42761981 | PubTator, text mining | PubMed |
| FGFR2 fusion as the key to targeted therapy - a case report with a diagnostic turning point. | Klin Onkol | 2026 | 42663156 | PubTator, text mining | PubMed |
| Urinary proteomic signature of exercise intolerance in patients at risk of heart failure: evidence from the HOMAGE trial. | EBioMedicine | 2026 | 42531722 | PubTator, text mining | PubMed |
| TACC3, correlated with immune cell infiltrates, is a novel prognostic biomarker in BRCA. | Medicine (Baltimore) | 2026 | 42499031 | PubTator, text mining | PubMed |
| Cross-Tissue Transcriptome-Wide Association Study Prioritizes Candidate Genes and Compound-Associated Signatures for Osteoarthritis. | Curr Pharm Des | 2026 | 42381324 | PubTator, text mining | PubMed |
| Identification of a novel PANoptosis-associated prognostic signature and immune landscape analysis in neuroblastoma with experimental validation. | Front Immunol | 2026 | 42273677 | PubTator, text mining | PubMed |
| A Multi-omics Investigation Identifies TACC3 as a Driver of Immunosuppression in Intrahepatic Cholangiocarcinoma via Activation of the STAT3-PD-L1 Axis. | J Clin Transl Hepatol | 2026 | 42181836 | PubTator, text mining | PubMed |
| The scaffold protein PRR14L is linked to mitotic fidelity and sensitivity to MPS1 inhibition. | Mol Biol Cell | 2026 | 42160513 | PubTator, text mining | PubMed |
| Development of an extended version of GALEAS bladder: Detection of FGFR3 fusions in urine and associations between genomic alterations and gene expression. | Bladder Cancer | 2026 | 42124891 | PubTator, text mining | PubMed |
| Nationwide genomic data analysis of central nervous system tumors in Japan based on C-CAT database. | Int J Clin Oncol | 2026 | 42089945 | PubTator, text mining | PubMed |
1 to 10 of 1,759
See all 1,759 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10460
GET https://conductscience.org/api/genes/v1/10460/patents?page=2