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Gene · 10487

CAP1: cyclase associated actin cytoskeleton regulatory protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAP1: cyclase associated actin cytoskeleton regulatory protein 1. Genes, record 10487. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10487

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Gene

Symbol
CAP1
HGNC
Name
cyclase associated actin cytoskeleton regulatory protein 1
HGNC
NCBI Gene ID
10487
NCBI Gene
HGNC ID
HGNC:20040
HGNC
Ensembl
ENSG00000131236
NCBI Gene
Aliases
CAP, CAP1-PEN
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01518Adenylyl cyclase-associated protein 14755Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199177Q01518Espacenet
JP 2025138725 A2025-09-252435Q01518Espacenet
JP 2025138725 A2025-09-252437Q01518Espacenet
JP 2025138725 A2025-09-252440Q01518Espacenet
JP 2025517970 A2025-06-129177Q01518Espacenet
JP 2025062604 A2025-04-1411545Q01518Espacenet
JP 2025062604 A2025-04-1411546Q01518Espacenet
JP 2025062604 A2025-04-1411549Q01518Espacenet
US 11884978 B22024-01-30451Q01518Espacenet
JP 2023145599 A2023-10-112435Q01518Espacenet

1 to 10 of 58

See all 58 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,163

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAP1 papersNewest fiscal year
P20GM103429Partnerships for Biomedical Research in Arkansas82025
ZIABC010661Vaccine and Drug Combination Therapy for Human Cancers72025
P30CA008748Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
P30DK034854Integrated Epithelial and Muscosal Biology52025
P30GM124165NE-CAT: A Resource for Advanced Macromolecular Crystallography52025
R35GM118086Mechanistic studies of nucleic acid enzymes involved in DNA replication, transcription, and innate immunity52025
ZIABC010778HIV-1 Maturation Inhibitors and Capsid Inhibitors52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P20GM113132The Institute for Biomolecular Targeting32025

1 to 10 of 1,163Source NIH's project files

See all 1,163 nih grants

Papers1,759

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Resistin in Tissue Remodeling and Fibrosis: A New Frontier.Biomolecules202642650776PubTator, text miningPubMed
Single-cell study reveals early alterations in peripheral blood immune responses at day 7 following microwave ablation for lung cancer.Cell Immunol202642551135PubTator, text miningPubMed
Retraction notice to "Molecular and cellular mechanisms of PDAC progression based on RETN-CAP1-mediated macrophage-fibroblast crosstalk: Action of ITGB5 and ITGB1 recombinant proteins" [Int. J. Biol. Macromol. 290 (2025) 139078].
Int J Biol Macromol202642527175PubTator, text miningPubMed
E2F1 Drives Endothelial Arterial Programming in Pulmonary Arterial Hypertension.bioRxiv202642465492PubTator, text miningPubMed
Altered Resting-State Co-Activation Patterns in Obsessive-Compulsive Disorder.Neuroimage202642448253PubTator, text miningPubMed
Identification and functional characterization of an mRNA Cap3 methyltransferase from Acanthamoeba castellani medusavirusi.J Biol Chem202642349786PubTator, text miningPubMed
CAPtivating toxins: Molecular evolution of CAP proteins (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1) in the chemical arsenals of diverse venomous animals.Toxicon202642341845PubTator, text miningPubMed
Configurational Fragility of Forest Landscapes Under Multiple Anthropic Uses.Ecol Evol202642292542PubTator, text miningPubMed
Thio-modification effects on mRNA translation using a PureCap-based capping method.RSC Chem Biol202642282264PubTator, text miningPubMed
Piecing together the alveolar-capillary unit: arterial-venous capillary polarization.Am J Physiol Lung Cell Mol Physiol202642227649PubTator, text miningPubMed

1 to 10 of 1,759

See all 1,759 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10487

GET https://conductscience.org/api/genes/v1/10487/patents?page=2