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Gene · 10516

FBLN5: fibulin 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FBLN5: fibulin 5. Genes, record 10516. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10516

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Gene

Symbol
FBLN5
HGNC
Name
fibulin 5
HGNC
NCBI Gene ID
10516
NCBI Gene
HGNC ID
HGNC:3602
HGNC
Ensembl
ENSG00000140092
NCBI Gene
Aliases
ADCL2, ARCL1A, ARMD3, CMT1H, DANCE, EVEC, FIBL-5, HNARMD, UP50
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UBX5Fibulin-54480Ensembl, GeneID, HGNC

Source UniProt

Patents51

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19234Q9UBX5Espacenet
JP 2026004568 A2026-01-1446319Q9UBX5Espacenet
EP 4650780 A22025-11-196940Q9UBX5Espacenet
EP 4641201 A22025-10-296791Q9UBX5Espacenet
JP 2025147176 A2025-10-065143Q9UBX5Espacenet
JP 2025529142 A2025-09-046345Q9UBX5Espacenet
US 12371689 B22025-07-296345Q9UBX5Espacenet
JP 2025517969 A2025-06-126791Q9UBX5Espacenet
JP 2025517970 A2025-06-126940Q9UBX5Espacenet
JP 2025028160 A2025-02-285143Q9UBX5Espacenet

1 to 10 of 51

See all 51 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants927

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFBLN5 papersNewest fiscal year
P20GM103446Delaware INBRE32025
P30CA086862Cancer Center Support Grant32025
P30EY010572Ophthalmology Core Facility32025
R01EY024942THE UBIQUITIN PATHWAY IN CORNEAL SCARRING32025
ZIAAG007380CLINICAL PROJECT: Age, Gene/Environment Susceptibility Study on the Multi-omics of Aging: A clinical epidemiologic prospective study32025
I01BX003644Upstream regulation of TAZ and YAP in sarcomas: Towards combinatorial therapytargeting the Hippo pathway22025
K12HD000850Pediatric Scientist Development Program22025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens22025
P01HL114501Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers22025
P20GM113126Nebraska Center for Integrated Biomolecular Communication (CIBC)22025

1 to 10 of 927Source NIH's project files

See all 927 nih grants

Papers1,386

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Statement of Retraction: Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5).Bioengineered202642821366PubTator, text miningPubMed
FGF23 blockade induces maladaptive vascular remodelling, reducing pathologically increased arterial stiffness and blood pressure.Nephrol Dial Transplant202642784441PubTator, text miningPubMed
Connective tissue and genetics in the pathogenesis of rectal prolapse: A scoping review.Colorectal Dis202642765168PubTator, text miningPubMed
Integrative transcriptomic analysis identifies ACP5 and FBLN5 as candidate shared transcriptomic signatures between pulpitis and carotid plaque rupture.Sci Rep202642744917PubTator, text miningPubMed
Retraction notice to "Protein interaction network drive more group integrated analytic larynx hub protein markers: LYVE1/FBLN5/INMT/DCN/ZFY/RSPO3 protein macromolecule collaborative diagnosis of a new era" [Int. J. Biol. Macromol. 315 (2025) 144586].
Int J Biol Macromol202642552209PubTator, text miningPubMed
miR-1911-3p Regulates Malignant Biological Behaviors and Glycolytic Activity of Triple-Negative Breast Cancer via FBLN5.Breast Cancer (Dove Med Press)202642517063PubTator, text miningPubMed
Late-Onset Preeclampsia Is Linked to Extensive Remodeling of the Placental Extracellular Matrix.Med Sci (Basel)202642506333PubTator, text miningPubMed
Genetic susceptibility to obesity-related asthma and its modulation by sequelae of obesity.bioRxiv202642395418PubTator, text miningPubMed
Identification of fibulin-5 as a granzyme B substrate involved in UVB-induced elastic fiber disruption.J Invest Dermatol202642331310PubTator, text miningPubMed
Exploring hypoxia-related genes as prognostic indicators in lung adenocarcinoma.PLoS One202642234659PubTator, text miningPubMed

1 to 10 of 1,386

See all 1,386 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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