Gene · 10522
DEAF1: DEAF1 transcription factor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DEAF1: DEAF1 transcription factor. Genes, record 10522. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10522
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75398 | Deformed epidermal autoregulatory factor 1 homolog | 565 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 10554 | O75398 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10904 | O75398 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4097 | O75398 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14869 | O75398 | Espacenet |
| JP 2025138725 A | 2025-09-25 | 2588 | O75398 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6127 | O75398 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6127 | O75398 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10904 | O75398 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10554 | O75398 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 4097 | O75398 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,104
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DEAF1 papers | Newest fiscal year |
|---|---|---|---|
| P51OD011132 | Emory National Primate Research Center | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01DA059993 | CRCNS: Decision dynamics in cortico-basal ganglia-thalamic networks | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P20GM109036 | Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases | 3 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| R01MH060379 | Functional and anatomical characterization of the striosomal system | 3 | 2025 |
| R01MH101221 | Rare Mutations and Autism Spectrum Disorders | 3 | 2025 |
| R37NS034696 | Dopaminergic and Muscarinic Signaling in the Striatum | 3 | 2025 |
1 to 10 of 1,104Source NIH's project files
See all 1,104 nih grantsPapers1,328
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Elucidating the role of DEAF1 in neurodevelopment and shared molecular pathways in high-risk autism genes using cortical organoids. | Sci Adv | 2026 | 42726852 | PubTator, text mining | PubMed |
| [Genetic and phenotypic analysis of three children with Neurodevelopmental disorders due to variants of DEAF1 gene]. | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | 2026 | 42711128 | PubTator, text mining | PubMed |
| Single-cell Atlas Reveals Myelopoietic Bias and Immunosuppressive Reprogramming in Metastatic Bone Marrow Across Cancers. | Genomics Proteomics Bioinformatics | 2026 | 42675604 | PubTator, text mining | PubMed |
| Cell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cells. | J Cell Sci | 2026 | 42599021 | PubTator, text mining | PubMed |
| Arsenic exposure disrupts human hematopoiesis by impairing the generation and function of hematopoietic stem and progenitor cells. | Environ Toxicol Pharmacol | 2026 | 42364718 | PubTator, text mining | PubMed |
| Neuroelectrophysiological clinical exploration of reward expectation and sensitivity abnormalities in adolescent melancholic MDD. | J Affect Disord | 2026 | 42285528 | PubTator, text mining | PubMed |
| Ascending propriospinal modulation of thoracic sympathetic preganglionic neurons during lumbar locomotor activity. | Front Neural Circuits | 2026 | 41939969 | PubTator, text mining | PubMed |
| A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium. | EBioMedicine | 2026 | 41875497 | PubTator, text mining | PubMed |
| Activity-Dependent Regulation of Basal Forebrain Cholinergic Neurons by Striatal Spiny Projection Neurons. | J Neurosci | 2026 | 41775628 | PubTator, text mining | PubMed |
| A Numerical Comparison of Petri Net and Ordinary Differential Equation SIR Component Models. | IEEE Access | 2026 | 41743905 | PubTator, text mining | PubMed |
1 to 10 of 1,328
See all 1,328 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10522
GET https://conductscience.org/api/genes/v1/10522/patents?page=2