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Gene · 10524

KAT5: lysine acetyltransferase 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KAT5: lysine acetyltransferase 5. Genes, record 10524. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10524

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Gene

Symbol
KAT5
HGNC
Name
lysine acetyltransferase 5
HGNC
NCBI Gene ID
10524
NCBI Gene
HGNC ID
HGNC:5275
HGNC
Ensembl
ENSG00000172977
NCBI Gene
Aliases
ESA1, HTATIP, HTATIP1, NEDFASB, PLIP, TIP, TIP60, ZC2HC5, cPLA2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92993Histone acetyltransferase KAT55133Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450518Q92993Espacenet
EP 4650780 A22025-11-199872Q92993Espacenet
JP 2025147176 A2025-10-0615193Q92993Espacenet
JP 2025517970 A2025-06-129872Q92993Espacenet
JP 2025028160 A2025-02-2815193Q92993Espacenet
KR 1020250010750 A2025-01-2115193Q92993Espacenet
WO 2024240908 A12024-11-281Q92993Espacenet
JP 2024109657 A2024-08-1415032Q92993Espacenet
US 11597924 B22023-03-0774Q92993Espacenet
US 11446398 B22022-09-2042404Q92993Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,858

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKAT5 papersNewest fiscal year
P30CA016672Cancer Center Support Grant202025
P30CA008748Cancer Center Support Grant132025
P30CA010815Consolidated Basic Cancer Research Program132025
R01CA198279Shaping DNA Damage Response Networks Via Histone H2A Variants102025
P30CA016086Cancer Center Support Grant92025
P30CA086862Cancer Center Support Grant92025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82025
P30CA076292Moffitt Cancer Center Support Grant82025
R01CA142861Renewal: HPV and the DNA Damage Response82025
R01NS095799Mechanisms underlying Tip60 HAT action in neuroprotection of cognitive function72025

1 to 10 of 2,858Source NIH's project files

See all 2,858 nih grants

Papers3,850

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
USP10 stabilizes FOXM1 through KAT5-mediated acetylation to suppress cell senescence and promote melanoma malignant progression.Int J Biol Sci202642807929PubTator, text miningPubMed
A mini-review of the molecular mechanisms, mutational landscape, and therapeutic opportunities of TWIST1 in oncology.Biochim Biophys Acta Mol Cell Res202642785447PubTator, text miningPubMed
Microenvironment-derived acetylated amino acids promote glioblastoma treatment resistance.Res Sq202642780293PubTator, text miningPubMed
[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex.Int J Oncol202642757459PubTator, text miningPubMed
KAT5: the epigenetic regulator of central nervous system diseases.Front Mol Neurosci202642756899PubTator, text miningPubMed
Target-level interpretability and diagnostic framework for molecular docking behavior in antimicrobial resistance research using probe ligands.J Mol Graph Model202642753477PubTator, text miningPubMed
An H2A.Z-dependent epigenetic checkpoint in macrophages couples genetic risk to microbial metabolite signaling.Protein Cell202642745483PubTator, text miningPubMed
Structure-guided identification and experimental validation of NAT10-targeting small molecules in colorectal cancer cells.J Comput Aided Mol Des202642742862PubTator, text miningPubMed
WSSV exploits host glycolytic reprogramming to promote hemocyanin lactylation and enhance cell-associated WSSV levels in shrimp.Fish Shellfish Immunol202642722174PubTator, text miningPubMed
TIP60-mediated acetylation of UHRF1 is associated with tumor cell-dependent M2-like macrophage phenotypes and aggressiveness in gastric cardia adenocarcinoma.Biochim Biophys Acta Mol Basis Dis202642722134PubTator, text miningPubMed

1 to 10 of 3,850

See all 3,850 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10524

GET https://conductscience.org/api/genes/v1/10524/patents?page=2