ConductScience.org, home

Gene · 10549

PRDX4: peroxiredoxin 4

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PRDX4: peroxiredoxin 4. Genes, record 10549. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10549

On this page

Gene

Symbol
PRDX4
HGNC
Name
peroxiredoxin 4
HGNC
NCBI Gene ID
10549
NCBI Gene
HGNC ID
HGNC:17169
HGNC
Ensembl
ENSG00000123131
NCBI Gene
Aliases
AOE37-2, AOE372, HEL-S-97n, PRX-4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13162Peroxiredoxin-427114Ensembl, GeneID, HGNC

Source UniProt

Patents88

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910146Q13162Espacenet
JP 2025147176 A2025-10-0610753Q13162Espacenet
JP 2025138725 A2025-09-252557Q13162Espacenet
JP 2025529142 A2025-09-047423Q13162Espacenet
WO 2025163153 A22025-08-0745Q13162Espacenet
US 12371689 B22025-07-297423Q13162Espacenet
JP 2025517970 A2025-06-1210146Q13162Espacenet
JP 2025028160 A2025-02-2810753Q13162Espacenet
KR 1020250010750 A2025-01-2110753Q13162Espacenet
JP 2024109657 A2024-08-1410760Q13162Espacenet

1 to 10 of 88

See all 88 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants781

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRDX4 papersNewest fiscal year
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant42025
P30CA012197Cancer Center Support Grant32025
P30ES001247Environmental Agents as Modulators of Disease Processes32025
R01AG044034Oxidative Stress and the Development of Osteoarthritis32025
P20GM103476Mississippi INBRE22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA008748Cancer Center Support Grant22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA016058Cancer Center Support Grant22025

1 to 10 of 781Source NIH's project files

See all 781 nih grants

Papers1,420

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Research progress on the characterization, evolution and functions of molluscan peroxiredoxins.Dev Comp Immunol202642810604PubTator, text miningPubMed
A Risk Prediction Model for Normal-Tension Glaucoma Progression Integrating Genetic Markers and Corneal Biomechanics.Semin Ophthalmol202642635405PubTator, text miningPubMed
Identification and Validation of an E2F Targets-Related Gene Signature Risk Score Predicting the Prognosis of Patients with Uveal Melanoma.Ocul Oncol Pathol202642553888PubTator, text miningPubMed
Comparative Evaluation of Serum Peroxiredoxin 2 (PRDX2), Serum Peroxiredoxin 4 (PRDX4), and Plasma Methylated Septin 9 (mSEPT9) Levels Against Conventional Biomarkers for Early Detection of Colorectal Cancer: A Study Protocol.
Cureus202642404326PubTator, text miningPubMed
Shared Transcriptomic Signatures and Network Interactions Between Lung Adenocarcinoma and Asthma.Int J Mol Sci202642353258PubTator, text miningPubMed
Bulk RNA sequencing identifies biomarkers for mitochondrial and programmed cell death in keloids.Burns202642314404PubTator, text miningPubMed
From tooth to gut: Proteomic evidence of systemic dysregulation in fluorosis.Ecotoxicol Environ Saf202642202465PubTator, text miningPubMed
Isoform-specific expression of peroxiredoxins in human cancer cell lines with various radioresistance.Free Radic Res202642172000PubTator, text miningPubMed
Iron: Regulation, redox homeostasis, and ferroptosis in cancer.Ferroptosis Oxid Stress202642099806PubTator, text miningPubMed
Serum phosphoproteome alterations associated with cardiac troponin I levels in acute myocardial infarction.Turk J Med Sci202642058992PubTator, text miningPubMed

1 to 10 of 1,420

See all 1,420 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10549

GET https://conductscience.org/api/genes/v1/10549/patents?page=2