Gene · 10575
CCT4: chaperonin containing TCP1 subunit 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CCT4: chaperonin containing TCP1 subunit 4. Genes, record 10575. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10575
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P50991 | T-complex protein 1 subunit delta | 539 | 66 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40950 | P50991 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11146 | P50991 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11146 | P50991 | Espacenet |
| JP 2024009871 A | 2024-01-23 | 62 | P50991 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 14448 | P50991 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 117419 | P50991 | Espacenet |
| JP 2021521876 A | 2021-08-30 | 76 | P50991 | Espacenet |
| WO 2019211343 A1 | 2019-11-07 | 62 | P50991 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 221385 | P50991 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 221385 | P50991 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants893
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CCT4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 6 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| ZIADK043403 | Inhibition Of Renal Injury | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 3 | 2025 |
| R01CA148706 | Targeting the colchicine binding site in tubulin for cancer therapy | 3 | 2025 |
| R35GM136321 | Accurate Molecular Decision Making during Protein Biogenesis | 3 | 2025 |
| T32EY025202 | Visual Sciences T32 | 3 | 2025 |
1 to 10 of 893Source NIH's project files
See all 893 nih grantsPapers1,376
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Biodistribution of Phosphorothioate-Based Antisense Oligonucleotides in Stabilin Receptor Knock-Out Models. | Nucleic Acid Ther | 2026 | 42547962 | PubTator, text mining | PubMed |
| TRiC-assisted folding of class I HDAC family proteins regulated by distinct co-chaperone and cofactor networks. | Sci Adv | 2026 | 42455925 | PubTator, text mining | PubMed |
| Comprehensive analysis of small GTPases in Microsporidia reveals new extremes in eukaryotic cell biology. | BMC Biol | 2026 | 42186014 | PubTator, text mining | PubMed |
| Chaperonin in health and disease. | Mol Biomed | 2026 | 41920440 | PubTator, text mining | PubMed |
| Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination. | Cell Death Discov | 2026 | 41872167 | PubTator, text mining | PubMed |
| Spatial Heterogeneity of Microbial Communities and Biogeochemical Function in Water Column of Site F Cold Seep, South China Sea. | Microb Ecol | 2026 | 41857392 | PubTator, text mining | PubMed |
| Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target. | Aging Cell | 2026 | 41786630 | PubTator, text mining | PubMed |
| The potential cytotoxic effect of recent universal adhesives with modified monomeric compositions on human gingival epithelial cells. | Sci Rep | 2026 | 41735380 | PubTator, text mining | PubMed |
| Sea-level changes modulate beach face slope in coastal upwelling zones. | Sci Rep | 2026 | 41720970 | PubTator, text mining | PubMed |
| Temperature and sex ratios at birth. | Proc Natl Acad Sci U S A | 2026 | 41712633 | PubTator, text mining | PubMed |
1 to 10 of 1,376
See all 1,376 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10575
GET https://conductscience.org/api/genes/v1/10575/patents?page=2