Gene · 10578
GNLY: granulysin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GNLY: granulysin. Genes, record 10578. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10578
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22749 | Granulysin | 145 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents89
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2263 | P22749 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6077 | P22749 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6516 | P22749 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6516 | P22749 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2263 | P22749 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 6077 | P22749 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 6077 | P22749 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6373 | P22749 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 6084 | P22749 | Espacenet |
| JP 2024096708 A | 2024-07-17 | 5 | P22749 | Espacenet |
1 to 10 of 89
See all 89 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,192
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GNLY papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001863 | Yale Clinical and Translational Science Award | 21 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 18 | 2025 |
| R01AI022553 | Molecular Analysis of Host Immune Response in Leprosy | 14 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| R01AR040312 | CD1-restricted T-cell Responses in Skin | 12 | 2025 |
| P30AI110527 | Tennessee Center for AIDS Research (TN-CFAR) | 10 | 2025 |
| U19AI057229 | Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro | 10 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 8 | 2025 |
| R01AR063759 | Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional state | 8 | 2025 |
| T32AI007290 | Molecular and Cellular Immunobiology | 8 | 2025 |
1 to 10 of 2,192Source NIH's project files
See all 2,192 nih grantsPapers3,745
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Fast and slow gene expression changes in blood following acute social stress. | Brain Behav Immun Health | 2026 | 42824708 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing reveals compartment-specific immune and tumor cell states in a contiguous spinal metastasis. | Neurooncol Adv | 2026 | 42757049 | PubTator, text mining | PubMed |
| Single-Cell Profiling Links T-Cell Accumulation and TH2/TH17 Dynamics to Eosinophilic Esophagitis (EoE) Activity in Children. | Allergy | 2026 | 42744607 | PubTator, text mining | PubMed |
Pre-transplant whole blood transcriptomic profiling identifies mRNAs linked to cirrhosis-associated immune dysfunction as candidate predictors of clinical outcomes after liver transplantation: an exploratory study. | Transpl Int | 2026 | 42729608 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing reveals distinct immune interaction networks in primary and reactivated HHV-6B infection. | J Infect Dis | 2026 | 42682208 | PubTator, text mining | PubMed |
| Transcriptomic Markers of Immunosenescence in Cynomolgus Macaques: A Pilot Study. | Genes (Basel) | 2026 | 42650137 | PubTator, text mining | PubMed |
| Menstruation is Associated With Cyclical Granulysin Peaks in Vaginal Secretions Despite Stable Expression by Cervicovaginal Immune Cells. | Am J Reprod Immunol | 2026 | 42616268 | PubTator, text mining | PubMed |
| Vγ9Vδ2 T cells in tuberculosis: protective immunity and translational perspectives. | Front Immunol | 2026 | 42609836 | PubTator, text mining | PubMed |
| Cytotoxic CD4+ T Cells in Visceral Leishmaniasis Patients. | Parasite Immunol | 2026 | 42609202 | PubTator, text mining | PubMed |
| Immunomodulatory effects of HUC-MSCs therapy: enhancing adaptive and innate immune responses in aging frailty. | Front Immunol | 2026 | 42564874 | PubTator, text mining | PubMed |
1 to 10 of 3,745
See all 3,745 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10578
GET https://conductscience.org/api/genes/v1/10578/patents?page=2