Gene · 1059
CENPB: centromere protein B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CENPB: centromere protein B. Genes, record 1059. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1059
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07199 | Major centromere autoantigen B | 599 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4698223 A2 | 2026-02-25 | 35 | P07199 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 40824 | P07199 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10211 | P07199 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10211 | P07199 | Espacenet |
| JP 2024530931 A | 2024-08-27 | 33 | P07199 | Espacenet |
| EP 4380580 A2 | 2024-06-12 | 33 | P07199 | Espacenet |
| KR 1020240083171 A | 2024-06-11 | 33 | P07199 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 13879 | P07199 | Espacenet |
| JP 2022538760 A | 2022-09-06 | 15 | P07199 | Espacenet |
| JP 2022077016 A | 2022-05-20 | 3 | P07199 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants931
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CENPB papers | Newest fiscal year |
|---|---|---|---|
| ZIABC010413 | Human Artificial Chromosomes for Cancer Research and Functional Genomics | 18 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 11 | 2025 |
| R01GM074728 | Mechanisms of Kinetochore Assembly | 7 | 2025 |
| R35GM122475 | Cell Biological mechanisms of centromere drive | 6 | 2025 |
| T32AR048522 | Multidisciplinary Rheumatology Training Program | 6 | 2025 |
| ZIABC011207 | Biomechanical properties of chromatin in cancer and normal cells | 6 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 5 | 2025 |
| R35GM122476 | Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis | 5 | 2025 |
| R35GM130302 | Centromere identity, strength, and regulation | 5 | 2025 |
| T32CA009110 | Training in Areas Fundamental to Cancer Research | 5 | 2025 |
1 to 10 of 931Source NIH's project files
See all 931 nih grantsPapers1,705
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Utility of an extended 12-autoantibody panel in systemic sclerosis: Clinical and prognostic implications in a real-life cohort. | Rev Clin Esp (Barc) | 2026 | 42772597 | PubTator, text mining | PubMed |
| Diagnostic performance of antibodies against extractable nuclear antigens detected by immunoblot in the differentiation of connective tissue diseases. | Allergol Immunopathol (Madr) | 2026 | 42760884 | PubTator, text mining | PubMed |
| Autoantibodies in systemic sclerosis display a proinflammatory Fc glycosylation signature independent of systemic inflammation. | J Autoimmun | 2026 | 42732745 | PubTator, text mining | PubMed |
| Anti-centromere antibody positivity: a spectrum of clinical diagnoses and immunological patterns in a large patient cohort. | Clin Rheumatol | 2026 | 42618734 | PubTator, text mining | PubMed |
| In-depth evaluation of false-positive biological reactions in the syphilis serological diagnosis: a cross-sectional study with two sampling components. | Front Cell Infect Microbiol | 2026 | 42591135 | PubTator, text mining | PubMed |
| Diagnostic performance of Pictor's targeted proteomics assay for extractable nuclear antigens compared with commercial line immunoassay and addressable laser bead immunoassay platforms. | J Immunol Methods | 2026 | 42456928 | PubTator, text mining | PubMed |
| A case analysis of Gitelman syndrome complicated with Sjögren's disease. | Front Med (Lausanne) | 2026 | 42404579 | PubTator, text mining | PubMed |
| Rapid centromere turnover and the adaptive radiation of lemurs. | bioRxiv | 2026 | 42239255 | PubTator, text mining | PubMed |
| CENP-B: Cornerstone of Kinetochores in Centromeres of Human Chromosomes. | Front Biosci (Landmark Ed) | 2026 | 42216547 | PubTator, text mining | PubMed |
| MNGIE with TYMP and POLG variants presenting as decade-long capsule retention: A case report. | Neurol Sci | 2026 | 42185572 | PubTator, text mining | PubMed |
1 to 10 of 1,705
See all 1,705 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1059
GET https://conductscience.org/api/genes/v1/1059/patents?page=2