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Gene · 1060

CENPC: centromere protein C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CENPC: centromere protein C. Genes, record 1060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1060

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Gene

Symbol
CENPC
HGNC
Name
centromere protein C
HGNC
NCBI Gene ID
1060
NCBI Gene
HGNC ID
HGNC:1854
HGNC
Ensembl
ENSG00000145241
NCBI Gene
Aliases
CENP-C, CENPC1, MIF2, hcp-4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03188Centromere protein C94317Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4698223 A22026-02-2536Q03188Espacenet
JP 2026004568 A2026-01-1440826Q03188Espacenet
EP 4650780 A22025-11-192875Q03188Espacenet
EP 4641201 A22025-10-292443Q03188Espacenet
JP 2025517969 A2025-06-122443Q03188Espacenet
JP 2025517970 A2025-06-122875Q03188Espacenet
JP 2023123507 A2023-09-0582Q03188Espacenet
US 11446398 B22022-09-2013880Q03188Espacenet
JP 2022077016 A2022-05-204Q03188Espacenet
JP 2022524081 A2022-04-27116851Q03188Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants680

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCENPC papersNewest fiscal year
R01GM074728Mechanisms of Kinetochore Assembly162025
ZIABC010413Human Artificial Chromosomes for Cancer Research and Functional Genomics152025
ZIABC011207Biomechanical properties of chromatin in cancer and normal cells112025
R35GM126930Molecular Analysis of Kinetochore Function92025
UL1TR001863Yale Clinical and Translational Science Award92025
ZIABC011209Formation of Centromeres in vivo92025
R01GM074215Kinetochore Specification and Function82025
R35GM130302Centromere identity, strength, and regulation82025
R35GM130365Mechanisms of Kinetochore-Microtubule Attachment and Regulation62025
ZIABC010822Molecular Determinants of Chromosome Transmission and Cell Cycle Regulation62025

1 to 10 of 680Source NIH's project files

See all 680 nih grants

Papers1,344

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The CENP-A chaperone complex spatially organizes centromeres.Sci Adv202642715337PubTator, text miningPubMed
Whole-Genome Resequencing-Based Selection-Signal and Association Analyses Prioritize Candidate Genes and Haplotypes for PRRS Resistance-Related Traits in Pigs.Animals (Basel)202642511095PubTator, text miningPubMed
Structural basis of βKNL2 centromeric targeting mechanism and its role in plant-specific kinetochore assembly.Nucleic Acids Res202642345193PubTator, text miningPubMed
Telomeric heterochromatin acts in trans to promote meiotic centromere assembly via Aurora B kinase recruitment.bioRxiv202642327281PubTator, text miningPubMed
CENP-B: Cornerstone of Kinetochores in Centromeres of Human Chromosomes.Front Biosci (Landmark Ed)202642216547PubTator, text miningPubMed
Exploring the Chemotactic Effects of MIF on Neutrophils and T Cells and Methods for Selective Receptor Targeting.Methods Mol Biol202642129120PubTator, text miningPubMed
Using 4-HPP and PP as Substrates to Assess Purified MIF and D-DT Tautomerase Activity and Inhibition.Methods Mol Biol202642129116PubTator, text miningPubMed
Analysis of D-Dopachrome Tautomerase Conformational Flexibility Through Molecular Dynamics Simulations.Methods Mol Biol202642129113PubTator, text miningPubMed
Detection of Noncovalent Protein-Ligand Complexes of D-DT Variants by MALDI-TOF Mass Spectrometry.Methods Mol Biol202642129112PubTator, text miningPubMed
Generation of High-Quality D-Dopachrome Tautomerase Crystals for Structural Studies.Methods Mol Biol202642129110PubTator, text miningPubMed

1 to 10 of 1,344

See all 1,344 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1060

GET https://conductscience.org/api/genes/v1/1060/patents?page=2