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Gene · 10611

PDLIM5: PDZ and LIM domain 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PDLIM5: PDZ and LIM domain 5. Genes, record 10611. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10611

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Gene

Symbol
PDLIM5
HGNC
Name
PDZ and LIM domain 5
HGNC
NCBI Gene ID
10611
NCBI Gene
HGNC ID
HGNC:17468
HGNC
Ensembl
ENSG00000163110
NCBI Gene
Aliases
ENH, ENH1, Enh, L9, LIM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96HC4PDZ and LIM domain protein 55963Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195396Q96HC4Espacenet
EP 4640849 A22025-10-29763Q96HC4Espacenet
EP 4641201 A22025-10-294991Q96HC4Espacenet
JP 2025529142 A2025-09-043433Q96HC4Espacenet
US 12371689 B22025-07-293433Q96HC4Espacenet
JP 2025519096 A2025-06-24763Q96HC4Espacenet
JP 2025517969 A2025-06-124991Q96HC4Espacenet
JP 2025517970 A2025-06-125396Q96HC4Espacenet
JP 2024123008 A2024-09-107563Q96HC4Espacenet
US 11446398 B22022-09-2061609Q96HC4Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,612

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePDLIM5 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant72025
P30CA006973Regional Oncology Research Center62025
R01HL058758Molecular basis of ILK-mediated cell adhesion52025
P30CA042014Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA016086Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025

1 to 10 of 1,612Source NIH's project files

See all 1,612 nih grants

Papers1,922

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular Characterization and Genetic Diversity of Helicobacter pylori bab Adhesin Gene Variants: Clinicopathological Associations.Diagnostics (Basel)202642793825PubTator, text miningPubMed
Single-Cell and Bulk RNA-Seq Profiling Identifies Cell Adhesion-Related Gene Signatures in Cerebral Ischemia-Reperfusion Injury.eNeuro202642791187PubTator, text miningPubMed
NEAT1 Coordinates a PDLIM5-CACNA1C Regulatory Program Associated with a Potentially Arrhythmogenic Cardiomyocyte State in the Border Zone During Early Myocardial Infarction.Int J Mol Sci202642737842PubTator, text miningPubMed
Proteasome inhibition alleviates proteinuria in Lmx1b knock-in mice with dysfunctional LIM domains.Nat Commun202642722687PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
A plasma protein signature for cerebral amyloid angiopathy.Acta Neuropathol202642162487PubTator, text miningPubMed
Emerging Mechanobiological Roles of LIM-Only Proteins: Distinct Pathways of CRP and LMO in Cytoskeleton Regulation and Disease.Cytoskeleton (Hoboken)202642129964PubTator, text miningPubMed
Sex-biased transcriptomic landscapes in bipolar disorder: integrating neurobiology and clinical heterogeneity through cross-study meta-analysis.Biol Sex Differ202642104453PubTator, text miningPubMed
AAK1-mediated phosphorylation of PDLIM5 and Talin1 promotes focal adhesion disassembly to accelerate cell migration.Nat Commun202642082516PubTator, text miningPubMed
Oncogenic LPP facilitates focal adhesion maturation in response to mechanical tension and regulates the Hippo signaling.Oncogene202641912774PubTator, text miningPubMed

1 to 10 of 1,922

See all 1,922 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10611

GET https://conductscience.org/api/genes/v1/10611/patents?page=2