Gene · 10618
TGOLN2: trans-golgi network protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TGOLN2: trans-golgi network protein 2. Genes, record 10618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10618
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O43493 | Trans-Golgi network integral membrane protein 2 | 437 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67581 | O43493 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9911 | O43493 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4659 | O43493 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4659 | O43493 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9911 | O43493 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 765 | O43493 | Espacenet |
| JP 2023554542 A | 2023-12-27 | 74 | O43493 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 90248 | O43493 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 3495 | O43493 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 193219 | O43493 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,206
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TGOLN2 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 23 | 2025 |
| R01GM083144 | Characterization of mammalian COG complex-interacting Golgi trafficking machinery | 16 | 2025 |
| R37GM058615 | Mechanisms and Physiology of COPI Transport | 7 | 2025 |
| R01EY015625 | Hermansky-Pudlak syndrome and melanosome formation | 5 | 2025 |
| K08NS123552 | Development of a Translational Research Platform to Understand and treat Defective Protein Trafficking in Childhood-Onset Hereditary Spastic Paraplegia | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 3 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,206Source NIH's project files
See all 1,206 nih grantsPapers1,565
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cell-cycle-resolved τSTED nanoscopy reveals nanoscale reorganization of TGN46-positive structures. | Cell Struct Funct | 2026 | 42732940 | PubTator, text mining | PubMed |
| Rab10 coordinates SADS-CoV non-lytic egress through the ERGIC-TGN-lysosome trafficking pathway. | PLoS Pathog | 2026 | 42678995 | PubTator, text mining | PubMed |
| SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism. | Cell Rep | 2026 | 42287635 | PubTator, text mining | PubMed |
| WNT2B impairs endosomal trafficking via WASHC5 to inhibit autophagy: a novel non-secretory WNT pathway. | Autophagy | 2026 | 42233622 | PubTator, text mining | PubMed |
| Exosome-like biogenesis from the Golgi releases extracellular vesicles lacking conventional tetraspanins that mediate immune evasion in cancer. | bioRxiv | 2026 | 42182266 | PubTator, text mining | PubMed |
| Novel Frameshift Variant in SORL1 Gene Identified in a EOAD Family Causes APP Sorting Dysfunction and Endolysosomal Swelling. | Mol Neurobiol | 2026 | 42149354 | PubTator, text mining | PubMed |
| A role for CASM in the repair of damaged Golgi architecture. | Autophagy | 2026 | 42115886 | PubTator, text mining | PubMed |
| CancerHubs Data Explorer: a web application for investigating mutation-enriched protein interaction hubs in human cancers. | BioData Min | 2026 | 41913220 | PubTator, text mining | PubMed |
| Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center. | Sci Adv | 2026 | 41894512 | PubTator, text mining | PubMed |
| The Open Reading Frame 7b of the SARS-CoV-2 Disperse Trans-Golgi and Activate the NLRP3 Inflammasome. | J Med Virol | 2026 | 41891494 | PubTator, text mining | PubMed |
1 to 10 of 1,565
See all 1,565 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10618
GET https://conductscience.org/api/genes/v1/10618/patents?page=2