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Gene · 10618

TGOLN2: trans-golgi network protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TGOLN2: trans-golgi network protein 2. Genes, record 10618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10618

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Gene

Symbol
TGOLN2
HGNC
Name
trans-golgi network protein 2
HGNC
NCBI Gene ID
10618
NCBI Gene
HGNC ID
HGNC:15450
HGNC
Ensembl
ENSG00000152291
NCBI Gene
Aliases
TGN38, TGN46, TGN48, TGN51, TTGN2, hTGN46, hTGN48, hTGN51
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43493Trans-Golgi network integral membrane protein 24371Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467581O43493Espacenet
EP 4650780 A22025-11-199911O43493Espacenet
JP 2025529142 A2025-09-044659O43493Espacenet
US 12371689 B22025-07-294659O43493Espacenet
JP 2025517970 A2025-06-129911O43493Espacenet
US 11884978 B22024-01-30765O43493Espacenet
JP 2023554542 A2023-12-2774O43493Espacenet
US 11446398 B22022-09-2090248O43493Espacenet
US 11400116 B22022-08-023495O43493Espacenet
JP 2022524081 A2022-04-27193219O43493Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,206

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTGOLN2 papersNewest fiscal year
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System232025
R01GM083144Characterization of mammalian COG complex-interacting Golgi trafficking machinery162025
R37GM058615Mechanisms and Physiology of COPI Transport72025
R01EY015625Hermansky-Pudlak syndrome and melanosome formation52025
K08NS123552Development of a Translational Research Platform to Understand and treat Defective Protein Trafficking in Childhood-Onset Hereditary Spastic Paraplegia42025
P30CA016672Cancer Center Support Grant42025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.32025
P30CA016059Massey Cancer Center - Cancer Center Support Grant32025
P30CA118100University of New Mexico Cancer Center Support Grant32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025

1 to 10 of 1,206Source NIH's project files

See all 1,206 nih grants

Papers1,565

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cell-cycle-resolved τSTED nanoscopy reveals nanoscale reorganization of TGN46-positive structures.Cell Struct Funct202642732940PubTator, text miningPubMed
Rab10 coordinates SADS-CoV non-lytic egress through the ERGIC-TGN-lysosome trafficking pathway.PLoS Pathog202642678995PubTator, text miningPubMed
SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism.Cell Rep202642287635PubTator, text miningPubMed
WNT2B impairs endosomal trafficking via WASHC5 to inhibit autophagy: a novel non-secretory WNT pathway.Autophagy202642233622PubTator, text miningPubMed
Exosome-like biogenesis from the Golgi releases extracellular vesicles lacking conventional tetraspanins that mediate immune evasion in cancer.bioRxiv202642182266PubTator, text miningPubMed
Novel Frameshift Variant in SORL1 Gene Identified in a EOAD Family Causes APP Sorting Dysfunction and Endolysosomal Swelling.Mol Neurobiol202642149354PubTator, text miningPubMed
A role for CASM in the repair of damaged Golgi architecture.Autophagy202642115886PubTator, text miningPubMed
CancerHubs Data Explorer: a web application for investigating mutation-enriched protein interaction hubs in human cancers.BioData Min202641913220PubTator, text miningPubMed
Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center.Sci Adv202641894512PubTator, text miningPubMed
The Open Reading Frame 7b of the SARS-CoV-2 Disperse Trans-Golgi and Activate the NLRP3 Inflammasome.J Med Virol202641891494PubTator, text miningPubMed

1 to 10 of 1,565

See all 1,565 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10618

GET https://conductscience.org/api/genes/v1/10618/patents?page=2