Gene · 1062
CENPE: centromere protein E
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CENPE: centromere protein E. Genes, record 1062. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1062
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q02224 | Centromere-associated protein E | 2,701 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40827 | Q02224 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2031 | Q02224 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4589 | Q02224 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2031 | Q02224 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4589 | Q02224 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 329 | Q02224 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 13884 | Q02224 | Espacenet |
| US 11401555 B2 | 2022-08-02 | 93 | Q02224 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 116855 | Q02224 | Espacenet |
| US 11248268 B2 | 2022-02-15 | 1 | Q02224 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,179
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CENPE papers | Newest fiscal year |
|---|---|---|---|
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 24 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 13 | 2025 |
| R01GM074215 | Kinetochore Specification and Function | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 6 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 5 | 2025 |
| ZIABC010413 | Human Artificial Chromosomes for Cancer Research and Functional Genomics | 5 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 4 | 2025 |
1 to 10 of 1,179Source NIH's project files
See all 1,179 nih grantsPapers2,042
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Approach for Castration and Enzalutamide Resistant Prostate Cancer. | Cancer Res | 2026 | 42757823 | PubTator, text mining | PubMed |
| PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses. | Cell Syst | 2026 | 42664975 | PubTator, text mining | PubMed |
| Condensation of MATCAP promotes CENP-E-dependent chromosome congression in mitosis. | Nat Commun | 2026 | 42660891 | PubTator, text mining | PubMed |
| Immune-related gene signature for predicting biochemical recurrence after RP in prostate cancer subtypes. | Discov Oncol | 2026 | 42635880 | PubTator, text mining | PubMed |
| An oxidative stress - and immunotherapy-related six-gene signature defines immune subtypes and predicts prognosis and immunotherapy response in hepatocellular carcinoma. | Gene | 2026 | 42551718 | PubTator, text mining | PubMed |
| Transcriptomic differences in chromatin and cell cycle regulation in A549 cells after irradiation with carbon ions and X-rays. | Front Oncol | 2026 | 42524029 | PubTator, text mining | PubMed |
| Targeting HASPIN-mediated H3T3 phosphorylation disrupts an epigenetic-kinesin axis to suppress colorectal cancer mitotic progression. | Mol Cancer | 2026 | 42415117 | PubTator, text mining | PubMed |
| Anisotropic unbinding and location-dependent hovering of a kinesin motor head over microtubule. | Biophys J | 2026 | 42381291 | PubTator, text mining | PubMed |
| PSMD8 promotes breast cancer progression and attenuates paclitaxel sensitivity by stabilizing KIF10. | Cancer Cell Int | 2026 | 42363209 | PubTator, text mining | PubMed |
| High-risk HPV E6 induces an aneuploidy-prone chromosome congression defect through destabilization of CENP-E. | J Virol | 2026 | 42200671 | PubTator, text mining | PubMed |
1 to 10 of 2,042
See all 2,042 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1062
GET https://conductscience.org/api/genes/v1/1062/patents?page=2