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Gene · 1062

CENPE: centromere protein E

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CENPE: centromere protein E. Genes, record 1062. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1062

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Gene

Symbol
CENPE
HGNC
Name
centromere protein E
HGNC
NCBI Gene ID
1062
NCBI Gene
HGNC ID
HGNC:1856
HGNC
Ensembl
ENSG00000138778
NCBI Gene
Aliases
CENP-E, KIF10, MCPH13, PPP1R61
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q02224Centromere-associated protein E2,7016Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440827Q02224Espacenet
EP 4641201 A22025-10-292031Q02224Espacenet
EP 4641202 A22025-10-294589Q02224Espacenet
JP 2025517969 A2025-06-122031Q02224Espacenet
KR 1020250017231 A2025-02-044589Q02224Espacenet
JP 2022141755 A2022-09-29329Q02224Espacenet
US 11446398 B22022-09-2013884Q02224Espacenet
US 11401555 B22022-08-0293Q02224Espacenet
JP 2022524081 A2022-04-27116855Q02224Espacenet
US 11248268 B22022-02-151Q02224Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,179

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCENPE papersNewest fiscal year
P30CA006927Comprehensive Cancer Center Program at Fox Chase242025
P30CA014520UW Comprehensive Cancer Center Support132025
R01GM074215Kinetochore Specification and Function82025
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant72025
P30CA023108Cancer Center Support Grant62025
P30CA015704Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
ZIABC010413Human Artificial Chromosomes for Cancer Research and Functional Genomics52025
P50CA097186The Pacific Northwest Prostate Cancer SPORE42025

1 to 10 of 1,179Source NIH's project files

See all 1,179 nih grants

Papers2,042

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Approach for Castration and Enzalutamide Resistant Prostate Cancer.Cancer Res202642757823PubTator, text miningPubMed
PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses.Cell Syst202642664975PubTator, text miningPubMed
Condensation of MATCAP promotes CENP-E-dependent chromosome congression in mitosis.Nat Commun202642660891PubTator, text miningPubMed
Immune-related gene signature for predicting biochemical recurrence after RP in prostate cancer subtypes.Discov Oncol202642635880PubTator, text miningPubMed
An oxidative stress - and immunotherapy-related six-gene signature defines immune subtypes and predicts prognosis and immunotherapy response in hepatocellular carcinoma.Gene202642551718PubTator, text miningPubMed
Transcriptomic differences in chromatin and cell cycle regulation in A549 cells after irradiation with carbon ions and X-rays.Front Oncol202642524029PubTator, text miningPubMed
Targeting HASPIN-mediated H3T3 phosphorylation disrupts an epigenetic-kinesin axis to suppress colorectal cancer mitotic progression.Mol Cancer202642415117PubTator, text miningPubMed
Anisotropic unbinding and location-dependent hovering of a kinesin motor head over microtubule.Biophys J202642381291PubTator, text miningPubMed
PSMD8 promotes breast cancer progression and attenuates paclitaxel sensitivity by stabilizing KIF10.Cancer Cell Int202642363209PubTator, text miningPubMed
High-risk HPV E6 induces an aneuploidy-prone chromosome congression defect through destabilization of CENP-E.J Virol202642200671PubTator, text miningPubMed

1 to 10 of 2,042

See all 2,042 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1062

GET https://conductscience.org/api/genes/v1/1062/patents?page=2