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TXNIP: thioredoxin interacting protein

1 protein, 33 patents, 0 drugs, 0 trials, 2,644 NIH grants and 5,123 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTXNIPHGNC
Namethioredoxin interacting proteinHGNC
NCBI Gene ID10628NCBI Gene
HGNC IDHGNC:16952HGNC
EnsemblENSG00000265972NCBI Gene
AliasesARRDC6, EST01027, HHCPA78, THIF, VDUP1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9H3M7Thioredoxin-interacting protein39111Ensembl, GeneID, HGNCUniProt

Patents 33

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1917452Q9H3M7Espacenet
EP 4641201 A22025-10-2921532Q9H3M7Espacenet
EP 4641202 A22025-10-298829Q9H3M7Espacenet
JP 2025517969 A2025-06-1221532Q9H3M7Espacenet
JP 2025517970 A2025-06-1217452Q9H3M7Espacenet
JP 2025032204 A2025-03-1137909Q9H3M7Espacenet
KR 1020250017231 A2025-02-048829Q9H3M7Espacenet
EP 4461818 A22024-11-1337909Q9H3M7Espacenet
JP 2024123008 A2024-09-108655Q9H3M7Espacenet
US 11974990 B22024-05-072Q9H3M7Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2644

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant152,025NIH's project files
P30CA016672Cancer Center Support Grant152,025NIH's project files
P30CA042014Cancer Center Support Grant112,025NIH's project files
P30DK079626UAB Diabetes Research Center102,025NIH's project files
P30EY004068Core Grant for Vision Research102,025NIH's project files
P30DK020579Diabetes Research Center92,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes72,025NIH's project files
P30CA016042Cancer Center Support Grant72,025NIH's project files

Papers 5123

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42811126PubTator, text miningPubMed
42810627PubTator, text miningPubMed
42810144PubTator, text miningPubMed
42792134PubTator, text miningPubMed
42789010PubTator, text miningPubMed
42774375PubTator, text miningPubMed
42759114PubTator, text miningPubMed
42739042PubTator, text miningPubMed
42721011PubTator, text miningPubMed
42720298PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license