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Gene · 10642

IGF2BP1: insulin like growth factor 2 mRNA binding protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGF2BP1: insulin like growth factor 2 mRNA binding protein 1. Genes, record 10642. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10642

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Gene

Symbol
IGF2BP1
HGNC
Name
insulin like growth factor 2 mRNA binding protein 1
HGNC
NCBI Gene ID
10642
NCBI Gene
HGNC ID
HGNC:28866
HGNC
Ensembl
ENSG00000159217
NCBI Gene
Aliases
CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NZI8Insulin-like growth factor 2 mRNA-binding protein 15772Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449916Q9NZI8Espacenet
EP 4641201 A22025-10-293004Q9NZI8Espacenet
JP 2025147176 A2025-10-0615855Q9NZI8Espacenet
WO 2025125557 A12025-06-199Q9NZI8Espacenet
JP 2025517969 A2025-06-123004Q9NZI8Espacenet
JP 2025028160 A2025-02-2815855Q9NZI8Espacenet
KR 1020250010750 A2025-01-2115855Q9NZI8Espacenet
JP 2024109657 A2024-08-1415694Q9NZI8Espacenet
US 12023371 B22024-07-024648Q9NZI8Espacenet
US 11946082 B22024-04-0223Q9NZI8Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,445

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGF2BP1 papersNewest fiscal year
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases102025
R01NS083085Mechanism of mRNA Localization and Localized Translation in Neurons92025
P30CA014520UW Comprehensive Cancer Center Support82025
P30CA016672Cancer Center Support Grant72025
P30CA016520Abramson Cancer Center Support Grant52025
P30CA013330Cancer Center Support Grant42025
P30CA016058Cancer Center Support Grant42025
R01AI110221The Cell Biology of HIV-1 Genome Trafficking42025
RM1HG008935Center for dynamic RNA epitranscriptomes - Renewal42025
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis42025

1 to 10 of 1,445Source NIH's project files

See all 1,445 nih grants

Papers3,895

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A tripartite mechanism licenses RNA polymerase import into the phage nucleus.bioRxiv202642818118PubTator, text miningPubMed
IGF2BP1-Mediated m6A Modification Enhances the Stability of circ_0088302 to Promote Gastric Cancer Progression.Adv Biol (Weinh)202642802600PubTator, text miningPubMed
IGF2BP1: a double agent in hemoglobin switching.Blood202642783360PubTator, text miningPubMed
Epitranscriptomic stabilization of PGRMC1 by the METTL3-IGF2BP1 axis promotes ovarian cancer progression.Cell Signal202642777928PubTator, text miningPubMed
H3K18la facilitates nasopharyngeal carcinoma progression through the activation of the IGF2BP1-COX2 signaling pathway.Front Immunol202642774366PubTator, text miningPubMed
Stress granule phase transitions and neuronal fate in cerebral ischemia-reperfusion injury.Front Mol Neurosci202642769600PubTator, text miningPubMed
[Preliminary exploration of BBOX1-AS1 as a potential biomarker involved in the regulation of tumor cell proliferation in non-small cell lung cancer].Zhonghua Zhong Liu Za Zhi202642764220PubTator, text miningPubMed
Epitranscriptomic Regulation of Cardiac Ischemia-Reperfusion Injury: Unveiling the METTL14/IGF2BP1/PDE4D Axis.Korean Circ J202642750131PubTator, text miningPubMed
Helicobacter pylori-Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis.Adv Sci (Weinh)202642725716PubTator, text miningPubMed
Mapping Allele-specific RBP Binding by a Machine Learning Coupled RNA Editing Strategy in Human Embryonic Stem Cells.Genomics Proteomics Bioinformatics202642671340PubTator, text miningPubMed

1 to 10 of 3,895

See all 3,895 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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