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Gene · 10658

CELF1: CUGBP Elav-like family member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CELF1: CUGBP Elav-like family member 1. Genes, record 10658. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10658

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Gene

Symbol
CELF1
HGNC
Name
CUGBP Elav-like family member 1
HGNC
NCBI Gene ID
10658
NCBI Gene
HGNC ID
HGNC:2549
HGNC
Ensembl
ENSG00000149187
NCBI Gene
Aliases
BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92879CUGBP Elav-like family member 14868Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-263Q92879Espacenet
EP 4650780 A22025-11-197568Q92879Espacenet
JP 2025517970 A2025-06-127568Q92879Espacenet
JP 2025062601 A2025-04-1416Q92879Espacenet
US 11564998 B22023-01-315957Q92879Espacenet
US 11446398 B22022-09-2020708Q92879Espacenet
JP 2022524081 A2022-04-27123679Q92879Espacenet
JP 2022523514 A2022-04-2516Q92879Espacenet
WO 2020043864 A12020-03-05431Q92879Espacenet
US 10463751 B22019-11-055957Q92879Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,716

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCELF1 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)292025
R01DK057819Intestinal Mucosal Growth in Health and Surgical Diseases192025
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis132025
I01BX000332Posttranscriptional Control of Gut Mucosal Defense and Homeostasis112025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions102025
P30DK063491Diabetes Research Center (DRC)92025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study72025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease72025
U24AG041689THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE72025
U24AG056270National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)72025

1 to 10 of 1,716Source NIH's project files

See all 1,716 nih grants

Papers1,641

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Expression of Concern: The RNA-binding protein CUG-BP1 increases survivin expression in oesophageal cancer cells through enhanced mRNA stability.Biochem J202642496086PubTator, text miningPubMed
Targeting of Gpx8-CSF1 axis resets the immune milieu of lung tumor and overcomes resistance to anti-PD-1 therapy.Cell Death Differ202642448922PubTator, text miningPubMed
CELF2 Is a Tumor Suppressor That Modulates SLC7A11 and Promotes Ferroptosis in Stomach Adenocarcinoma.Mol Cancer Res202642307591PubTator, text miningPubMed
CELF2-dependent RNA Regulation Supports Cortical Architecture and Synaptic Stability During Early Brain Development.Mol Neurobiol202642189331PubTator, text miningPubMed
CELF family of RNA-binding proteins: roles in disease biology and potential for therapeutic intervention.Cell Commun Signal202642104406PubTator, text miningPubMed
Modification of internal RNA domains from the long non-coding RNA XIST refines roles in silencing and heterochromatin recruitment.Hum Mol Genet202641926242PubTator, text miningPubMed
Programmed cell death: a promising management for Alzheimer's disease.Apoptosis202641904723PubTator, text miningPubMed
Obesity and Cancer: From Systemic Metabolic Reprogramming to Immunotherapy Paradox.Metabolites202641893325PubTator, text miningPubMed
Mutual feedback regulation between Poly(A)-specific ribonuclease (PARN) and cognate microRNAs.Life Sci Alliance202641825960PubTator, text miningPubMed
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1).ChemMedChem202641797662PubTator, text miningPubMed

1 to 10 of 1,641

See all 1,641 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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