Gene · 107
ADCY1: adenylate cyclase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ADCY1: adenylate cyclase 1. Genes, record 107. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/107
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q08828 | Adenylate cyclase type 1 | 1,119 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents21
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36681 | Q08828 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3378 | Q08828 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3378 | Q08828 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 2782 | Q08828 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24091 | Q08828 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 24091 | Q08828 | Espacenet |
| KR 1020230136786 A | 2023-09-27 | 16 | Q08828 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 24091 | Q08828 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 2782 | Q08828 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4777 | Q08828 | Espacenet |
1 to 10 of 21
See all 21 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,527
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ADCY1 papers | Newest fiscal year |
|---|---|---|---|
| P30EY006360 | P30-Core Grant for Vision Research | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| R01NS045954 | Neuropeptidergic Inhibition of Spinal Pain Transmission | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 3 | 2025 |
| R01DC003594 | Identification of Autosomal Recessive Nonsyndromic Hearing Impairment Genes | 3 | 2025 |
1 to 10 of 1,527Source NIH's project files
See all 1,527 nih grantsPapers2,742
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Corrigendum to "Ginsenoside Rg1 alleviates cognitive impairment in vascular dementia by modulating Adcy1/Kdr-mediated cholinergic synapse and PI3K-AKT pathway" [Phytomedicine, 143 (2025) 156882]. | Phytomedicine | 2026 | 42749573 | PubTator, text mining | PubMed |
| Positive Feedback Mechanisms in Pain Modulation and Chronic Pain. | Eur J Neurosci | 2026 | 42742368 | PubTator, text mining | PubMed |
| Axially Chiral Nonalternant Polycyclic Aromatic Hydrocarbon With Consecutive Pentagons Exhibiting Large Spin-Polarized Current. | Angew Chem Int Ed Engl | 2026 | 42695227 | PubTator, text mining | PubMed |
| Safety, tolerability, and pharmacokinetics of oral FM888 in healthy Chinese adults: a Phase I, randomized, double-blind, placebo-controlled study. | Drug Dev Ind Pharm | 2026 | 42521322 | PubTator, text mining | PubMed |
| Evolution of CTCF binding sites in the human genome. | Mol Biol Evol | 2026 | 42412056 | PubTator, text mining | PubMed |
| Improving pancreatic adenocarcinoma prognosis models through ligand receptor interactions and histopathological integration. | J Transl Med | 2026 | 42399741 | PubTator, text mining | PubMed |
| Upregulation of adenylyl cyclase 1 is crucial for osteogenic and adipogenic differentiation of MSCs. | Cells Dev | 2026 | 42324028 | PubTator, text mining | PubMed |
| Exploring Molecular Dynamics and Structure Change of Dissolved Organic Nitrogen under Nitrate and Phosphate Pulses in a Cascade Upflow Biofiltration System. | Environ Sci Technol | 2026 | 42283698 | PubTator, text mining | PubMed |
| Inhibition of adenylyl cyclase 1 or exchange protein activated by cAMP restores ATP-sensitive potassium channel activity after chronic opioid exposure. | Br J Pharmacol | 2026 | 41946477 | PubTator, text mining | PubMed |
| Functional profiling of somatostatin receptors identifies somatostatin receptor subtype 2 as a vulnerability in Succinate Dehydrogenase SDHB-deficient pheochromocytomas and paragangliomas. | Mol Biomed | 2026 | 41928014 | PubTator, text mining | PubMed |
1 to 10 of 2,742
See all 2,742 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/107
GET https://conductscience.org/api/genes/v1/107/patents?page=2