ConductScience.org, home

Gene · 107

ADCY1: adenylate cyclase 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ADCY1: adenylate cyclase 1. Genes, record 107. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/107

On this page

Gene

Symbol
ADCY1
HGNC
Name
adenylate cyclase 1
HGNC
NCBI Gene ID
107
NCBI Gene
HGNC ID
HGNC:232
HGNC
Ensembl
ENSG00000164742
NCBI Gene
Aliases
AC1, DFNB44
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q08828Adenylate cyclase type 11,1190Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436681Q08828Espacenet
EP 4641201 A22025-10-293378Q08828Espacenet
JP 2025517969 A2025-06-123378Q08828Espacenet
JP 2025062604 A2025-04-142782Q08828Espacenet
JP 2025032204 A2025-03-1124091Q08828Espacenet
EP 4461818 A22024-11-1324091Q08828Espacenet
KR 1020230136786 A2023-09-2716Q08828Espacenet
JP 2023058610 A2023-04-2524091Q08828Espacenet
US 11446398 B22022-09-202782Q08828Espacenet
US 11400116 B22022-08-024777Q08828Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,527

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleADCY1 papersNewest fiscal year
P30EY006360P30-Core Grant for Vision Research62025
P30CA016672Cancer Center Support Grant52025
R01NS045954Neuropeptidergic Inhibition of Spinal Pain Transmission52025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA008748Cancer Center Support Grant32025
P30CA014195Cancer Center Support Grant (CCSG)32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA030199Cancer Center Support Grant (CCSG)32025
P30DK020593Vanderbilt Diabetes Research Center32025
R01DC003594Identification of Autosomal Recessive Nonsyndromic Hearing Impairment Genes32025

1 to 10 of 1,527Source NIH's project files

See all 1,527 nih grants

Papers2,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Corrigendum to "Ginsenoside Rg1 alleviates cognitive impairment in vascular dementia by modulating Adcy1/Kdr-mediated cholinergic synapse and PI3K-AKT pathway" [Phytomedicine, 143 (2025) 156882].Phytomedicine202642749573PubTator, text miningPubMed
Positive Feedback Mechanisms in Pain Modulation and Chronic Pain.Eur J Neurosci202642742368PubTator, text miningPubMed
Axially Chiral Nonalternant Polycyclic Aromatic Hydrocarbon With Consecutive Pentagons Exhibiting Large Spin-Polarized Current.Angew Chem Int Ed Engl202642695227PubTator, text miningPubMed
Safety, tolerability, and pharmacokinetics of oral FM888 in healthy Chinese adults: a Phase I, randomized, double-blind, placebo-controlled study.Drug Dev Ind Pharm202642521322PubTator, text miningPubMed
Evolution of CTCF binding sites in the human genome.Mol Biol Evol202642412056PubTator, text miningPubMed
Improving pancreatic adenocarcinoma prognosis models through ligand receptor interactions and histopathological integration.J Transl Med202642399741PubTator, text miningPubMed
Upregulation of adenylyl cyclase 1 is crucial for osteogenic and adipogenic differentiation of MSCs.Cells Dev202642324028PubTator, text miningPubMed
Exploring Molecular Dynamics and Structure Change of Dissolved Organic Nitrogen under Nitrate and Phosphate Pulses in a Cascade Upflow Biofiltration System.Environ Sci Technol202642283698PubTator, text miningPubMed
Inhibition of adenylyl cyclase 1 or exchange protein activated by cAMP restores ATP-sensitive potassium channel activity after chronic opioid exposure.Br J Pharmacol202641946477PubTator, text miningPubMed
Functional profiling of somatostatin receptors identifies somatostatin receptor subtype 2 as a vulnerability in Succinate Dehydrogenase SDHB-deficient pheochromocytomas and paragangliomas.Mol Biomed202641928014PubTator, text miningPubMed

1 to 10 of 2,742

See all 2,742 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/107

GET https://conductscience.org/api/genes/v1/107/patents?page=2