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CETP: cholesteryl ester transfer protein

1 protein, 62 patents, 6 drugs, 39 trials, 3,450 NIH grants and 7,659 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCETPHGNC
Namecholesteryl ester transfer proteinHGNC
NCBI Gene ID1071NCBI Gene
HGNC IDHGNC:1869HGNC
EnsemblENSG00000087237NCBI Gene
AliasesBPIFF, HDLCQ10NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P11597Cholesteryl ester transfer protein4933Ensembl, GeneID, HGNCUniProt

Patents 62

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441197P11597Espacenet
US 12509501 B22025-12-3030P11597Espacenet
EP 4650780 A22025-11-19209P11597Espacenet
EP 4640849 A22025-10-2927P11597Espacenet
EP 4641201 A22025-10-29177P11597Espacenet
JP 2025147176 A2025-10-062657P11597Espacenet
JP 2025529142 A2025-09-045835P11597Espacenet
US 12371689 B22025-07-295835P11597Espacenet
JP 2025519096 A2025-06-2427P11597Espacenet
JP 2025517969 A2025-06-12177P11597Espacenet

Drugs 6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ANACETRAPIBCHEMBL1800807Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL
DALCETRAPIBCHEMBL313006Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL
EVACETRAPIBCHEMBL2017179Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL
OBICETRAPIBCHEMBL3785197Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL
ROCACETRAPIBCHEMBL4297601Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL
TORCETRAPIBCHEMBL479527Cholesteryl ester transfer protein inhibitorINHIBITORChEMBL

Trials 39

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07219602OBICETRAPIBPHASE3ClinicalTrials.gov
NCT06496243OBICETRAPIBPHASE2ClinicalTrials.gov
NCT05425745OBICETRAPIBPHASE32025-06-11ClinicalTrials.gov
NCT05421078OBICETRAPIBPHASE22024-09-27ClinicalTrials.gov
NCT05266586OBICETRAPIBPHASE22024-07-03ClinicalTrials.gov
NCT05161715OBICETRAPIBPHASE22024-11-19ClinicalTrials.gov
NCT05142722OBICETRAPIBPHASE32025-09-19ClinicalTrials.gov
NCT04770389OBICETRAPIBPHASE22024-04-24ClinicalTrials.gov
NCT04753606OBICETRAPIBPHASE22024-06-11ClinicalTrials.gov
NCT04676867DALCETRAPIBPHASE22022-12-07ClinicalTrials.gov

NIH grants 3450

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK017047Diabetes Research Center342,025NIH's project files
P30DK063491Diabetes Research Center (DRC)332,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)162,025NIH's project files
P30DK035816Nutrition Obesity Research Center142,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center102,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center102,025NIH's project files
P01HL116263HDL Function in Human Disease92,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)92,025NIH's project files
P30DK079626UAB Diabetes Research Center92,025NIH's project files
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION92,025NIH's project files

Papers 7659

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42810526PubTator, text miningPubMed
42786013PubTator, text miningPubMed
42779867PubTator, text miningPubMed
42767172PubTator, text miningPubMed
42751822PubTator, text miningPubMed
42725613PubTator, text miningPubMed
42695295PubTator, text miningPubMed
42663147PubTator, text miningPubMed
42654259PubTator, text miningPubMed
42652126PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license