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CFL1: cofilin 1

1 protein, 118 patents, 0 drugs, 0 trials, 4,616 NIH grants and 8,173 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCFL1HGNC
Namecofilin 1HGNC
NCBI Gene ID1072NCBI Gene
HGNC IDHGNC:1874HGNC
EnsemblENSG00000172757NCBI Gene
AliasesCFL, HEL-S-15, cofilinNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P23528Cofilin-116619Ensembl, GeneID, HGNCUniProt

Patents 118

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194638P23528Espacenet
JP 2025517970 A2025-06-124638P23528Espacenet
JP 2024123008 A2024-09-105631P23528Espacenet
JP 2024123008 A2024-09-105632P23528Espacenet
JP 2024009871 A2024-01-2375P23528Espacenet
JP 2023064789 A2023-05-1265P23528Espacenet
WO 2023074712 A2023-05-0411P23528Espacenet
KR 1020220133109 A2022-10-0413P23528Espacenet
US 11446398 B22022-09-2018083P23528Espacenet
US 11446398 B22022-09-2018088P23528Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4616

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant202,025NIH's project files
P20GM103424Louisiana Biomedical Research Network162,025NIH's project files
P30CA008748Cancer Center Support Grant112,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE102,025NIH's project files
P30CA013330Cancer Center Support Grant92,025NIH's project files
R35GM136656Actin filament mechanics and branched network turnover92,025NIH's project files
P20GM103429Partnerships for Biomedical Research in Arkansas82,025NIH's project files
R01GM114666Molecular Mechanisms of Bacterial Toxins Targeting the Actin Cytoskeleton82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30CA023108Cancer Center Support Grant72,025NIH's project files

Papers 8173

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826616PubTator, text miningPubMed
42818273PubTator, text miningPubMed
42782769PubTator, text miningPubMed
42759326PubTator, text miningPubMed
42745872PubTator, text miningPubMed
42741318PubTator, text miningPubMed
42725794PubTator, text miningPubMed
42709792PubTator, text miningPubMed
42677823PubTator, text miningPubMed
42668575PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license