ConductScience.org, home

Library / Genes

OGA: O-GlcNAcase

1 protein, 34 patents, 0 drugs, 0 trials, 2,631 NIH grants and 8,432 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolOGAHGNC
NameO-GlcNAcaseHGNC
NCBI Gene ID10724NCBI Gene
HGNC IDHGNC:7056HGNC
EnsemblENSG00000198408NCBI Gene
AliasesMEA5, MGEA5, NCOATNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O60502Protein O-GlcNAcase91629Ensembl, GeneID, HGNCUniProt

Patents 34

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453254O60502Espacenet
EP 4650780 A22025-11-197955O60502Espacenet
EP 4641201 A22025-10-298047O60502Espacenet
JP 2025517969 A2025-06-128047O60502Espacenet
JP 2025517970 A2025-06-127955O60502Espacenet
WO 2025093745 A12025-05-08265O60502Espacenet
EP 4484957 A12025-01-01222O60502Espacenet
JP 2024019511 A2024-02-0924O60502Espacenet
JP 2023123507 A2023-09-0594O60502Espacenet
WO 2023162878 A2023-08-31222O60502Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2631

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIADK060103Enzymes of O-GlcNAc cycling linked to type-2 diabetes and neurodegeneration312,025NIH's project files
ZIADK060101Targeted disruption the enzymes of O-GlcNAc cycling: Animal models of Disease302,025NIH's project files
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair242,025NIH's project files
ZIADK060102Calmodulin-driven Nuclear Trafficking linked to diabetes and insulin signaling212,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)122,025NIH's project files
R01DK039773Mechanisms of Ischemic Kidney Injury and Repair122,025NIH's project files
R01GM121718Beyond the Active Site: Structure Informed Novel Regulatory Mechanisms and Functional Modulation of O-GlcNAc Transferase122,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
R01CA067985DNA Damage Repair by MUTYH and MUTYH Variants Associated with Colorectal Cancer92,025NIH's project files

Papers 8432

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819162PubTator, text miningPubMed
42815594PubTator, text miningPubMed
42793049PubTator, text miningPubMed
42788889PubTator, text miningPubMed
42784112PubTator, text miningPubMed
42783611PubTator, text miningPubMed
42774062PubTator, text miningPubMed
42765265PubTator, text miningPubMed
42761708PubTator, text miningPubMed
42755622PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license