Gene · 10725
NFAT5: nuclear factor of activated T cells 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NFAT5: nuclear factor of activated T cells 5. Genes, record 10725. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10725
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O94916 | Nuclear factor of activated T-cells 5 | 1,531 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents53
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025172069 A | 2025-11-20 | 784 | O94916 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7062 | O94916 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1038 | O94916 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6950 | O94916 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15359 | O94916 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1038 | O94916 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6950 | O94916 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7062 | O94916 | Espacenet |
| US 12247982 B2 | 2025-03-11 | 784 | O94916 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15359 | O94916 | Espacenet |
1 to 10 of 53
See all 53 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,210
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NFAT5 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| R01AI040127 | Signal transduction and gene induction in lymphocytes | 4 | 2025 |
| U54MD012392 | RCMI Center for Health Disparities Research | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P01AI039671 | Costimulatory Mechanisms of Autoimmunity | 3 | 2025 |
| P30DK097948 | The Cleveland Digestive Diseases Research Core Center (DDRCC) | 3 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 3 | 2025 |
| ZIAHL001285 | Solute And Water Transport In Renal Epithelia | 3 | 2025 |
| ZIAHL006129 | Computational Tools for Proteomics | 3 | 2025 |
1 to 10 of 1,210Source NIH's project files
See all 1,210 nih grantsPapers1,907
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Tonicity drives collecting duct maturation in the mammalian kidney. | Nat Commun | 2026 | 42827133 | PubTator, text mining | PubMed |
| Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart. | J Precis Med (Amst) | 2026 | 42644057 | PubTator, text mining | PubMed |
| Arecoline promotes oral submucous fibrosis by enhancing epithelial cell cuproptosis through PUS1-mediated pseudouridylation. | 3 Biotech | 2026 | 42523757 | PubTator, text mining | PubMed |
| Circular RNA circNUP214 serves as a microRNA-31 sponge to promote the progression of myasthenia gravis through NFAT5. | Front Neurol | 2026 | 42494400 | PubTator, text mining | PubMed |
| Integrated Transcriptomic Analysis Identifies Potential Biomarkers in Castration-Resistant Prostate Cancer. | World J Oncol | 2026 | 42490773 | PubTator, text mining | PubMed |
| LINC02207 suppresses breast cancer progression by promoting cuproptosis through NFAT5 regulation. | Biochim Biophys Acta Mol Basis Dis | 2026 | 42480769 | PubTator, text mining | PubMed |
| miR-543 targets NFAT5 in diabetic foot ulcer diagnosis and endothelial protection. | Arch Biochem Biophys | 2026 | 42480676 | PubTator, text mining | PubMed |
| Tumor-driven stabilization of CD8+ T cell exhaustion and implications for cancer immunotherapy. | Front Immunol | 2026 | 42433383 | PubTator, text mining | PubMed |
| Landscape of N6-methyladenosine (m6A) methylation in porcine cells identifies candidate genes associated with porcine epidemic diarrhea virus infection. | Front Microbiol | 2026 | 42232905 | PubTator, text mining | PubMed |
| Conserved Transcriptional Circuits Regulate Cardiac Fibroblast-Mediated Fibrosis. | Circ Res | 2026 | 42125800 | PubTator, text mining | PubMed |
1 to 10 of 1,907
See all 1,907 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10725
GET https://conductscience.org/api/genes/v1/10725/patents?page=2