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Gene · 10733

Papers2,106

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Skeletal muscle dedifferentiation requires centrosomes.NPJ Regen Med202642786221PubTator, text miningPubMed
The Centriole Biogenesis Cycle: Temporal Mechanisms, Autonomy and Coupling to the Cell Cycle and Other Cellular Clocks.Adv Exp Med Biol202642782439PubTator, text miningPubMed
CD20 targeted nanomedicine enhances anti-tumor immunity in diffuse large B-cell lymphoma by activating cGAS/STING pathway.Cancer Lett202642762966PubTator, text miningPubMed
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
Design, Synthesis, and Biological Activity Evaluation of Quinazoline-Based PLK4 Inhibitors.Biomedicines202642652193PubTator, text miningPubMed
Centriolar satellites regulate CEP350 mRNA stability and centrosome amplification.Mol Biol Cell202642555824PubTator, text miningPubMed
Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37-Amplified Neuroblastoma.J Med Chem202642463132PubTator, text miningPubMed
Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma.NPJ Precis Oncol202642432132PubTator, text miningPubMed
Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification.Cancer Cell Int202642316241PubTator, text miningPubMed
Two distinct causes contribute to the low efficiency of human pre-implantation development.Cell202642276044PubTator, text miningPubMed
Tipping the balance: synthesis and evaluation of centrinone-based degraders of polo-like kinase 4.RSC Chem Biol202642220890PubTator, text miningPubMed
GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4.Cell Death Differ202642185629PubTator, text miningPubMed
Centrosome depletion rewires mitosis to impose dependence on the AURKA-TPX2 axis.bioRxiv202642146378PubTator, text miningPubMed
Impact of Chromosomal Instability and Aneuploidy in Cancer Development.Annu Rev Cancer Biol202642137044PubTator, text miningPubMed
Maternal genetic variants associated with aneuploid conception: a narrative review.Hum Reprod Update202642124334PubTator, text miningPubMed
Cavitation-Free Acoustic Sensitization Enhances PLK4-Targeted Therapy Using the Phillyrin Derivative DE02 in Osteosarcoma.Cancer Biother Radiopharm202642099105PubTator, text miningPubMed
Migrasome-mediated clearance of PLK4: a novel mechanism for centrosome homeostasis and tumor targeting.EBioMedicine202642034049PubTator, text miningPubMed
RETRACTION: Polo-Like Kinase 4 Correlates With Greater Tumor Size, Lymph Node Metastasis, and Confers Poor Survival in Non-Small Cell Lung Cancer.J Clin Lab Anal202641972893PubTator, text miningPubMed
Targeting KIFC1 to disrupt centrosome clustering and trigger anaphase catastrophe in small-cell lung cancer.JCI Insight202641948931PubTator, text miningPubMed
TFEB-mediated autophagy dysregulation links with PRPF31 deficiency-induced photoreceptor death via PLK4 downregulation.Exp Eye Res202641932639PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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