Gene · 10735
STAG2: STAG2 cohesin complex component
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. STAG2: STAG2 cohesin complex component. Genes, record 10735. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10735
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8N3U4 | Cohesin subunit SA-2 | 1,231 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65659 | Q8N3U4 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 65661 | Q8N3U4 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 65662 | Q8N3U4 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9139 | Q8N3U4 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9139 | Q8N3U4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 84631 | Q8N3U4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 84633 | Q8N3U4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 84634 | Q8N3U4 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 187602 | Q8N3U4 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 187604 | Q8N3U4 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,492
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | STAG2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 72 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 35 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 18 | 2025 |
| U10CA180821 | Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension | 17 | 2025 |
| U24CA196171 | The Alliance NCTN Biorepository and Biospecimen Resource | 14 | 2025 |
| U10CA180882 | Alliance Statistics and Data Management Center | 13 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 11 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 10 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 9 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 9 | 2025 |
1 to 10 of 1,492Source NIH's project files
See all 1,492 nih grantsPapers2,605
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genomic and clinical determinants of response to Azacitidine plus venetoclax in acute myeloid leukemia: Results from the HM-SCREEN-Japan 02 study. | PLoS One | 2026 | 42821569 | PubTator, text mining | PubMed |
| Hidden Outcomes of CRISPR-Cas9 Genome Editing Revealed by Targeted Sequencing in Isogenic Human iPSC Clones. | CRISPR J | 2026 | 42817219 | PubTator, text mining | PubMed |
| The Role of STAG2, CDKN2A, and TP53 Genes in Ewing Sarcoma: A Report of a Rare Case of Primary Ewing Sarcoma of the Kidney With Favorable Outcome. | J Pediatr Hematol Oncol | 2026 | 42804587 | PubTator, text mining | PubMed |
| A CRISPR-Based Humanized Model Reveals Cooperative Role of STAG2 Loss in Familial GATA2-Deficient MDS Progression. | Blood Adv | 2026 | 42782284 | PubTator, text mining | PubMed |
| Co-occurrence of GATA2 deficiency and probable constitutional mosaic STAG2 alteration in a young adult with myelodysplastic syndrome: a case report. | Front Med (Lausanne) | 2026 | 42750708 | PubTator, text mining | PubMed |
| Serial VAF Kinetics Reveal Dynamic Clonal Evolution Associated With Progression in Clonal Cytopenia of Undetermined Significance. | Eur J Haematol | 2026 | 42728663 | PubTator, text mining | PubMed |
| A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies. | Clin Genet | 2026 | 42713681 | PubTator, text mining | PubMed |
| Appearances can be deceptive: acute myeloid leukaemia simulating chronic lymphocytic leukaemia. | Adv Lab Med | 2026 | 42713567 | PubTator, text mining | PubMed |
| GATA2: a small gene with big impact - a case report and literature review. | Acta Clin Belg | 2026 | 42703944 | PubTator, text mining | PubMed |
| Evaluation of HDAC8 as a Druggable Target in STAG2-Mutant Ewing Sarcoma. | ACS Chem Biol | 2026 | 42677456 | PubTator, text mining | PubMed |
1 to 10 of 2,605
See all 2,605 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10735
GET https://conductscience.org/api/genes/v1/10735/patents?page=2