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Gene · 10735

STAG2: STAG2 cohesin complex component

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. STAG2: STAG2 cohesin complex component. Genes, record 10735. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10735

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Gene

Symbol
STAG2
HGNC
Name
STAG2 cohesin complex component
HGNC
NCBI Gene ID
10735
NCBI Gene
HGNC ID
HGNC:11355
HGNC
Ensembl
ENSG00000101972
NCBI Gene
Aliases
HPE13, MKMS, NEDXCF, SA-2, SA2, SCC3B, bA517O1.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8N3U4Cohesin subunit SA-21,2319Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465659Q8N3U4Espacenet
JP 2026004568 A2026-01-1465661Q8N3U4Espacenet
JP 2026004568 A2026-01-1465662Q8N3U4Espacenet
EP 4641201 A22025-10-299139Q8N3U4Espacenet
JP 2025517969 A2025-06-129139Q8N3U4Espacenet
US 11446398 B22022-09-2084631Q8N3U4Espacenet
US 11446398 B22022-09-2084633Q8N3U4Espacenet
US 11446398 B22022-09-2084634Q8N3U4Espacenet
JP 2022524081 A2022-04-27187602Q8N3U4Espacenet
JP 2022524081 A2022-04-27187604Q8N3U4Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,492

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTAG2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant722025
P30CA016672Cancer Center Support Grant352025
P30CA016058Cancer Center Support Grant182025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension172025
U24CA196171The Alliance NCTN Biorepository and Biospecimen Resource142025
U10CA180882Alliance Statistics and Data Management Center132025
P30CA021765Cancer Center Support Grant (CCSG)112025
P30CA016056Roswell Park Cancer Center Support Grant102025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant92025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement92025

1 to 10 of 1,492Source NIH's project files

See all 1,492 nih grants

Papers2,605

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genomic and clinical determinants of response to Azacitidine plus venetoclax in acute myeloid leukemia: Results from the HM-SCREEN-Japan 02 study.PLoS One202642821569PubTator, text miningPubMed
Hidden Outcomes of CRISPR-Cas9 Genome Editing Revealed by Targeted Sequencing in Isogenic Human iPSC Clones.CRISPR J202642817219PubTator, text miningPubMed
The Role of STAG2, CDKN2A, and TP53 Genes in Ewing Sarcoma: A Report of a Rare Case of Primary Ewing Sarcoma of the Kidney With Favorable Outcome.J Pediatr Hematol Oncol202642804587PubTator, text miningPubMed
A CRISPR-Based Humanized Model Reveals Cooperative Role of STAG2 Loss in Familial GATA2-Deficient MDS Progression.Blood Adv202642782284PubTator, text miningPubMed
Co-occurrence of GATA2 deficiency and probable constitutional mosaic STAG2 alteration in a young adult with myelodysplastic syndrome: a case report.Front Med (Lausanne)202642750708PubTator, text miningPubMed
Serial VAF Kinetics Reveal Dynamic Clonal Evolution Associated With Progression in Clonal Cytopenia of Undetermined Significance.Eur J Haematol202642728663PubTator, text miningPubMed
A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.Clin Genet202642713681PubTator, text miningPubMed
Appearances can be deceptive: acute myeloid leukaemia simulating chronic lymphocytic leukaemia.Adv Lab Med202642713567PubTator, text miningPubMed
GATA2: a small gene with big impact - a case report and literature review.Acta Clin Belg202642703944PubTator, text miningPubMed
Evaluation of HDAC8 as a Druggable Target in STAG2-Mutant Ewing Sarcoma.ACS Chem Biol202642677456PubTator, text miningPubMed

1 to 10 of 2,605

See all 2,605 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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