Gene · 10840
ALDH1L1: aldehyde dehydrogenase 1 family member L1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALDH1L1: aldehyde dehydrogenase 1 family member L1. Genes, record 10840. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10840
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75891 | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 902 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37002 | O75891 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37005 | O75891 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11028 | O75891 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11454 | O75891 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11454 | O75891 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 11028 | O75891 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3850 | O75891 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3858 | O75891 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24390 | O75891 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24392 | O75891 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,307
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALDH1L1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK056350 | Nutrition Obesity Research Center (NORC) | 7 | 2025 |
| P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 5 | 2025 |
| P30CA072720 | Cancer Center Support Grant | 5 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 5 | 2025 |
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 4 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 4 | 2025 |
| R01DK126666 | Mechanistic and metabolomic underpinnings of ALDH1L1 polymorphisms in the regulation of glycine metabolism | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
| R01AA011147 | Ethanol and aldehyde dehydrogenases in health and disease | 3 | 2025 |
1 to 10 of 1,307Source NIH's project files
See all 1,307 nih grantsPapers1,409
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Dynamically Coupled Network-Guided Engineering of Amine Dehydrogenase With Cofactor Recycling for Efficient Biosynthesis of (R)-3-Aminobutanol. | Biotechnol Bioeng | 2026 | 42557781 | PubTator, text mining | PubMed |
| Folic acid prevention of neural tube defects requires retinoic acid produced by ALDH1L1. | Proc Natl Acad Sci U S A | 2026 | 42531027 | PubTator, text mining | PubMed |
| The mycobacterial selenocysteine machinery: presence and expression. | RNA Biol | 2026 | 42528383 | PubTator, text mining | PubMed |
| Detecting Vibrational Energy Transfer into an Enzyme Active Site via a Transition State Analog. | J Phys Chem Lett | 2026 | 42360871 | PubTator, text mining | PubMed |
| Microbial Responses and Metabolic Mechanisms During Anaerobic Degradation of N,N-Dimethylformamide by Co-Cultured Sludge. | Microorganisms | 2026 | 42354797 | PubTator, text mining | PubMed |
| Structural basis of regioselective double halogenation of the β-carboline tryptoline by the single-component halogenase AetF. | Acta Crystallogr D Struct Biol | 2026 | 42329691 | PubTator, text mining | PubMed |
| Transcriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma. | Front Cell Dev Biol | 2026 | 42326014 | PubTator, text mining | PubMed |
| Clinical implications of 10-formyltetrahydrofolate dehydrogenase expression in hormone receptor-positive breast cancer. | Front Oncol | 2026 | 42266668 | PubTator, text mining | PubMed |
| Electroenzymatic CO2 Reduction Through Hollow Covalent Organic Framework-Immobilized Enzyme With Neutral Red-Modified Electrode. | ChemSusChem | 2026 | 42213054 | PubTator, text mining | PubMed |
| Formate Dehydrogenase: The Role of the AMP Cofactor Fragment in Stabilization of the Transition State for Enzyme-Catalyzed Hydride Transfer. | ACS Omega | 2026 | 42146174 | PubTator, text mining | PubMed |
1 to 10 of 1,409
See all 1,409 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10840
GET https://conductscience.org/api/genes/v1/10840/patents?page=2