Gene · 10892
MALT1: MALT1 paracaspase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MALT1: MALT1 paracaspase. Genes, record 10892. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10892
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 824 | 26 | Ensembl, GeneID, HGNC |
Source UniProt
Patents85
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026086608 A | 2026-05-26 | 1 | Q9UDY8 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 54162 | Q9UDY8 | Espacenet |
| EP 4661970 A1 | 2025-12-17 | 62160 | Q9UDY8 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 535 | Q9UDY8 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19676 | Q9UDY8 | Espacenet |
| JP 2025524002 A | 2025-07-25 | 7 | Q9UDY8 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19676 | Q9UDY8 | Espacenet |
| KR 1020250039465 A | 2025-03-20 | 7 | Q9UDY8 | Espacenet |
| US 12247982 B2 | 2025-03-11 | 535 | Q9UDY8 | Espacenet |
| JP 2024028924 A | 2024-03-05 | 6 | Q9UDY8 | Espacenet |
1 to 10 of 85
See all 85 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,525
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MALT1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| ZIABC011008 | Oncogenic mechanisms and molecular targets in lymphoma | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 7 | 2025 |
| ZIASC000550 | Lymphoma Disease Discovery and Definition | 7 | 2025 |
| R01AI127564 | Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis | 6 | 2025 |
| ZIABC011070 | Hematopathology Diagnosis | 6 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 5 | 2025 |
| T32HL007622 | Boxer Training Program in Hematology | 5 | 2025 |
1 to 10 of 1,525Source NIH's project files
See all 1,525 nih grantsPapers2,863
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A phase 1, first-in-human study of safimaltib, a MALT1 inhibitor, in B-lymphocytic malignancies. | Blood Cancer Discov | 2026 | 42814116 | PubTator, text mining | PubMed |
| Running on Empty Signals: What Human MALT1 Deficiency Reveals About Immune Control. | J Immunol Res | 2026 | 42745540 | PubTator, text mining | PubMed |
| Targeting intracellular immune regulatory molecules for cancer immunotherapy in solid tumors. | Crit Rev Oncol Hematol | 2026 | 42732787 | PubTator, text mining | PubMed |
| Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease. | Int J Mol Med | 2026 | 42695408 | PubTator, text mining | PubMed |
| Novel agents and evolving strategies in Waldenström macroglobulinemia: clinical trial updates from ASH 2025. | Exp Hematol Oncol | 2026 | 42665819 | PubTator, text mining | PubMed |
| Epitranscriptomics, immunometabolism, and NETosis: unlocking novel mechanisms of traditional Chinese medicine in COPD. | Front Immunol | 2026 | 42614789 | PubTator, text mining | PubMed |
| A role for the protease MALT1 in EBV-mediated B-cell transformation by Latent Membrane Proteins 1 and 2. | Leukemia | 2026 | 42595846 | PubTator, text mining | PubMed |
| From Dynamics to Diagnosis and Therapy: A Multiscale Computational Framework for MALT1-Targeted Cancer Theranostics. | J Chem Inf Model | 2026 | 42573397 | PubTator, text mining | PubMed |
| [Clinicopathological features and prognosis of marginal zone lymphoma with aberrant CD10 expression]. | Zhonghua Bing Li Xue Za Zhi | 2026 | 42547419 | PubTator, text mining | PubMed |
| The requirement of MALT1 activity for the growth of adult T cell leukemia/lymphoma. | iScience | 2026 | 42542590 | PubTator, text mining | PubMed |
1 to 10 of 2,863
See all 2,863 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10892
GET https://conductscience.org/api/genes/v1/10892/patents?page=2