ConductScience.org, home

Gene · 10899

JTB: jumping translocation breakpoint

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. JTB: jumping translocation breakpoint. Genes, record 10899. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10899

On this page

Gene

Symbol
JTB
HGNC
Name
jumping translocation breakpoint
HGNC
NCBI Gene ID
10899
NCBI Gene
HGNC ID
HGNC:6201
HGNC
Ensembl
ENSG00000143543
NCBI Gene
Aliases
HJTB, HSPC222, PAR, hJT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O76095Protein JTB1461Ensembl, GeneID, HGNC

Source UniProt

Patents99

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450485O76095Espacenet
EP 4650780 A22025-11-192791O76095Espacenet
JP 2025529142 A2025-09-042184O76095Espacenet
US 12371689 B22025-07-292184O76095Espacenet
JP 2025517970 A2025-06-122791O76095Espacenet
US 11446398 B22022-09-2042355O76095Espacenet
US 11400116 B22022-08-023548O76095Espacenet
JP 2022524081 A2022-04-27145326O76095Espacenet
US 11078247 B22021-08-035681O76095Espacenet
JP 2019054813 A2019-04-11230920O76095Espacenet

1 to 10 of 99

See all 99 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,812

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleJTB papersNewest fiscal year
P30CA016672Cancer Center Support Grant142025
P01CA092584Structural Cell Biology of DNA Repair Machines92025
P30CA008748Cancer Center Support Grant82025
ZIAAR041205Integration of the results from systems-level determination of cis-acting elements into high-resolution maps of posttranscriptional regulatory events.82025
ZIABC011078Phase 0-1 Clinical Trials82025
P30CA056036Translational Research in Cancer72025
R01DK069710The Role of Nuclear PARPs in Signal-Regulated Transcription62025
P30CA047904Cancer Center Support Grant52025
P30CA118100University of New Mexico Cancer Center Support Grant42025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center42025

1 to 10 of 1,812Source NIH's project files

See all 1,812 nih grants

Papers2,553

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Inhibition of mitochondrial permeability transition selectively suppresses thrombogenic platelet procoagulant activity.Blood202642821743PubTator, text miningPubMed
Interceptive maxillary expansion in children in the early mixed dentition with maxillary anterior crowding.Eur J Paediatr Dent202642803211PubTator, text miningPubMed
Incremental Prognostic Value of Albumin-Anchored Inflammatory Ratios Beyond a SOFA-Based Model in a Medical ICU: A Retrospective Cohort Study.Metabolites202642783817PubTator, text miningPubMed
Influence of the menstrual cycle and sex hormones on the response to genotoxic stress in human cells.Toxicol Lett202642722046PubTator, text miningPubMed
RSF1-Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites.Adv Sci (Weinh)202642635688PubTator, text miningPubMed
5-FU in combination with PARP inhibitor ABT-888 deregulates MGMT-dependent mismatch repair (MMR) pathway in MMR-proficient colorectal cancer stem cells by modulating MGMT/PARP1/MSH6 complex.Expert Opin Ther Targets202642466612PubTator, text miningPubMed
Evolutionary dynamics of enlarged neo-sex chromosomes and novel pseudoautosomal regions in Sylvioidea songbirds.Commun Biol202642401675PubTator, text miningPubMed
External validation of American heart association predicting risk of cardiovascular disease EVENTs (PREVENT) equations in a Chinese population.Sci Rep202642393162PubTator, text miningPubMed
Prognostic Value of Maximal and Mean Lactate-to-Albumin (LAR), C-Reactive Protein-to-Albumin (CAR), and Procalcitonin-to-Albumin (PAR) Ratios Beyond ICU Admission in Critically Ill Patients.J Clin Med202642355864PubTator, text miningPubMed
D-Box Binding Protein (DBP) as a Circadian Output Regulator: Molecular Mechanisms, Tissue-Specific Functions, and Disease Relevance.Int J Mol Sci202642353162PubTator, text miningPubMed

1 to 10 of 2,553

See all 2,553 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10899

GET https://conductscience.org/api/genes/v1/10899/patents?page=2