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Gene · 109

ADCY3: adenylate cyclase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ADCY3: adenylate cyclase 3. Genes, record 109. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/109

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Gene

Symbol
ADCY3
HGNC
Name
adenylate cyclase 3
HGNC
NCBI Gene ID
109
NCBI Gene
HGNC ID
HGNC:234
HGNC
Ensembl
ENSG00000138031
NCBI Gene
Aliases
AC-III, AC3, BMIQ19
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60266Adenylate cyclase type 31,1440Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436687O60266Espacenet
EP 4650780 A22025-11-191813O60266Espacenet
EP 4640849 A22025-10-29217O60266Espacenet
EP 4641201 A22025-10-291396O60266Espacenet
JP 2025529142 A2025-09-04288O60266Espacenet
US 12371689 B22025-07-29288O60266Espacenet
JP 2025519096 A2025-06-24217O60266Espacenet
JP 2025517969 A2025-06-121396O60266Espacenet
JP 2025517970 A2025-06-121813O60266Espacenet
JP 2025062604 A2025-04-142794O60266Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,712

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleADCY3 papersNewest fiscal year
P30DK063491Diabetes Research Center (DRC)112025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)82025
R01DK075787Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum62025
P30ES010126UNC Center for Environmental Health and Susceptibility52025
T32HL007055Cardiovascular Epidemiology Training Grant52025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).52025
UL1TR001863Yale Clinical and Translational Science Award52025
P2CHD050924Carolina Population Center42025
P30CA016672Cancer Center Support Grant42025
U01AG009740Health and Retirement Study: Yrs 35-4042025

1 to 10 of 1,712Source NIH's project files

See all 1,712 nih grants

Papers1,451

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Bioactivity-Guided Optimization of 3-Deoxyanthocyanidin Extraction and Seasonal Mapping of Four Morphotypes of Fridericia chica (Bonpl.) L.G. Lohmann.Int J Mol Sci202642794621PubTator, text miningPubMed
Genome-wide mapping of common and rare variant effects on adiposity across childhood.Nat Genet202642791368PubTator, text miningPubMed
Cucurbit Leaf Crumple Virus: An Important Pathogen of Cucurbit and Snap Bean Crops.Mol Plant Pathol202642740504PubTator, text miningPubMed
Dynamic regulation of hypothalamic NPY2R-positive primary cilia by nutritional states.Front Cell Dev Biol202642591487PubTator, text miningPubMed
Shared Genetic Architecture and Pleiotropic Loci Linking Endometriosis and Inflammatory Bowel Disease: An Integrative GWAS, Colocalization, and Mendelian Randomization Study.Biomed Res Int202642515984PubTator, text miningPubMed
Phylogeographic Structure and Molecular Evolution of Squash Leaf Curl China Virus.Viruses202642515646PubTator, text miningPubMed
Peripheral blood CADM1 expression and multi-gene signatures in depressive disorders: a pilot case-control study from the United Arab Emirates.Front Psychiatry202642459288PubTator, text miningPubMed
AC3® exerts cytotoxic and anti-migratory activity and modulates the gene expression of TNF-α, inflammatory mediators, and components of the CD39/CD73/adenosine axis in cutaneous melanoma cell lines.Med Oncol202642455469PubTator, text miningPubMed
Primary Cilia as Integrative Hubs of Metabolic Signaling in Type 2 Diabetes: Inter-Organ Evidence From Central, Peripheral, and Pancreatic Islet Tissues.J Cell Physiol202642436646PubTator, text miningPubMed
Genotype-Phenotype Spectrum of Non-Syndromic Monogenic Obesity in a National Paediatric Cohort.Pediatr Obes202642210527PubTator, text miningPubMed

1 to 10 of 1,451

See all 1,451 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/109

GET https://conductscience.org/api/genes/v1/109/patents?page=2