Gene · 10914
PAPOLA: poly(A) polymerase alpha
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PAPOLA: poly(A) polymerase alpha. Genes, record 10914. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10914
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51003 | Poly(A) polymerase alpha | 745 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents17
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58352 | P51003 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 330 | P51003 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 247 | P51003 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3338 | P51003 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3338 | P51003 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 247 | P51003 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 330 | P51003 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 64655 | P51003 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 167626 | P51003 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 1764 | P51003 | Espacenet |
1 to 10 of 17
See all 17 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants973
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PAPOLA papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 4 | 2025 |
| P42ES013661 | Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation | 4 | 2025 |
| ZIABC010655 | Prostate Cancer Imaging | 4 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 3 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| R01DK069710 | The Role of Nuclear PARPs in Signal-Regulated Transcription | 3 | 2025 |
| R35GM128666 | Structure and regulation of lipid metabolism and transport | 3 | 2025 |
1 to 10 of 973Source NIH's project files
See all 973 nih grantsPapers2,273
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Probiotic-Derived Antimicrobial Proteins and Peptides: Molecular Mechanisms, Clinical Applications, and Future Therapeutic Perspectives. | Probiotics Antimicrob Proteins | 2026 | 42635917 | PubTator, text mining | PubMed |
| Cost-Related Barriers, Mental Distress, and Cervical Cancer Screening Adherence: A BRFSS 2024 Analysis. | J Prim Care Community Health | 2026 | 42544410 | PubTator, text mining | PubMed |
| A review of research progress on periplasmic adaptor proteins in bacterial tripartite pumps. | Front Microbiol | 2026 | 42404788 | PubTator, text mining | PubMed |
| Study on the influence of calreticulin on melasma based on bioinformatics. | Comput Methods Biomech Biomed Engin | 2026 | 42322614 | PubTator, text mining | PubMed |
| Cytomorphologic Findings Associated With High-Risk HPV Categories in PAP Smears. | Diagn Cytopathol | 2026 | 42216446 | PubTator, text mining | PubMed |
| Thermostable Chaperone Tag Fusion In Vitro: Development of TST-TE Complexes for Enhanced Enzyme Thermal Stability. | J Agric Food Chem | 2026 | 42215310 | PubTator, text mining | PubMed |
| Perisynaptic Astrocytic Processes as Communication Hubs and Early Sites of Dysfunction. | Neuroscientist | 2026 | 42183623 | PubTator, text mining | PubMed |
Characterization of Antimicrobial Resistance and Potential Zoonotic Risk in Uropathogenic Escherichia coli Isolated from Companion Animals, with Genomic Analysis of Virulence Determinants in a Representative Isolate. | Trop Med Infect Dis | 2026 | 42042961 | PubTator, text mining | PubMed |
| Controlling In Vitro mRNA Polyadenylation by Monitoring Poly(A) Polymerase Consumption of ATP. | Int J Mol Sci | 2026 | 41977116 | PubTator, text mining | PubMed |
| Novel Immunotherapeutic Strategies for Castration-Resistant Prostate Cancer: Mechanisms and Clinical Advances. | Curr Issues Mol Biol | 2026 | 41899434 | PubTator, text mining | PubMed |
1 to 10 of 2,273
See all 2,273 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10914
GET https://conductscience.org/api/genes/v1/10914/patents