ConductScience.org, home

Gene · 10914

PAPOLA: poly(A) polymerase alpha

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PAPOLA: poly(A) polymerase alpha. Genes, record 10914. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10914

On this page

Gene

Symbol
PAPOLA
HGNC
Name
poly(A) polymerase alpha
HGNC
NCBI Gene ID
10914
NCBI Gene
HGNC ID
HGNC:14981
HGNC
Ensembl
ENSG00000090060
NCBI Gene
Aliases
PAP, PAP-alpha
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51003Poly(A) polymerase alpha7451Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458352P51003Espacenet
EP 4650780 A22025-11-19330P51003Espacenet
EP 4641201 A22025-10-29247P51003Espacenet
JP 2025529142 A2025-09-043338P51003Espacenet
US 12371689 B22025-07-293338P51003Espacenet
JP 2025517969 A2025-06-12247P51003Espacenet
JP 2025517970 A2025-06-12330P51003Espacenet
US 11446398 B22022-09-2064655P51003Espacenet
JP 2022524081 A2022-04-27167626P51003Espacenet
WO 2020043864 A12020-03-051764P51003Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants973

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePAPOLA papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA008748Cancer Center Support Grant42025
P30ES005605Environmental Health Sciences Research Center42025
P42ES013661Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation42025
ZIABC010655Prostate Cancer Imaging42025
P30AI027763UCSF-Bay Area Center for AIDS Research32025
P30CA006973Regional Oncology Research Center32025
P30CA014520UW Comprehensive Cancer Center Support32025
R01DK069710The Role of Nuclear PARPs in Signal-Regulated Transcription32025
R35GM128666Structure and regulation of lipid metabolism and transport32025

1 to 10 of 973Source NIH's project files

See all 973 nih grants

Papers2,273

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Probiotic-Derived Antimicrobial Proteins and Peptides: Molecular Mechanisms, Clinical Applications, and Future Therapeutic Perspectives.Probiotics Antimicrob Proteins202642635917PubTator, text miningPubMed
Cost-Related Barriers, Mental Distress, and Cervical Cancer Screening Adherence: A BRFSS 2024 Analysis.J Prim Care Community Health202642544410PubTator, text miningPubMed
A review of research progress on periplasmic adaptor proteins in bacterial tripartite pumps.Front Microbiol202642404788PubTator, text miningPubMed
Study on the influence of calreticulin on melasma based on bioinformatics.Comput Methods Biomech Biomed Engin202642322614PubTator, text miningPubMed
Cytomorphologic Findings Associated With High-Risk HPV Categories in PAP Smears.Diagn Cytopathol202642216446PubTator, text miningPubMed
Thermostable Chaperone Tag Fusion In Vitro: Development of TST-TE Complexes for Enhanced Enzyme Thermal Stability.J Agric Food Chem202642215310PubTator, text miningPubMed
Perisynaptic Astrocytic Processes as Communication Hubs and Early Sites of Dysfunction.Neuroscientist202642183623PubTator, text miningPubMed
Characterization of Antimicrobial Resistance and Potential Zoonotic Risk in Uropathogenic Escherichia coli Isolated from Companion Animals, with Genomic Analysis of Virulence Determinants in a Representative Isolate.
Trop Med Infect Dis202642042961PubTator, text miningPubMed
Controlling In Vitro mRNA Polyadenylation by Monitoring Poly(A) Polymerase Consumption of ATP.Int J Mol Sci202641977116PubTator, text miningPubMed
Novel Immunotherapeutic Strategies for Castration-Resistant Prostate Cancer: Mechanisms and Clinical Advances.Curr Issues Mol Biol202641899434PubTator, text miningPubMed

1 to 10 of 2,273

See all 2,273 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10914

GET https://conductscience.org/api/genes/v1/10914/patents