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Gene · 10935

PRDX3: peroxiredoxin 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRDX3: peroxiredoxin 3. Genes, record 10935. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10935

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Gene

Symbol
PRDX3
HGNC
Name
peroxiredoxin 3
HGNC
NCBI Gene ID
10935
NCBI Gene
HGNC ID
HGNC:9354
HGNC
Ensembl
ENSG00000165672
NCBI Gene
Aliases
AOP-1, AOP1, HBC189, MER5, PPPCD, PRO1748, SCAR32, SP-22, prx-III
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30048Thioredoxin-dependent peroxide reductase, mitochondrial2562Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457387P30048Espacenet
EP 4650780 A22025-11-193880P30048Espacenet
WO 2025163153 A22025-08-0744P30048Espacenet
JP 2025517970 A2025-06-123880P30048Espacenet
JP 2024112982 A2024-08-214424P30048Espacenet
JP 2022184996 A2022-12-134424P30048Espacenet
US 11446398 B22022-09-2062023P30048Espacenet
JP 2022524081 A2022-04-27164994P30048Espacenet
US 11260081 B22022-03-014424P30048Espacenet
US 11078247 B22021-08-038903P30048Espacenet

1 to 10 of 53

See all 53 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,231

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRDX3 papersNewest fiscal year
P30CA012197Cancer Center Support Grant62025
P30ES019776HERCULES: Exposome Research Center52025
P30CA008748Cancer Center Support Grant42025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant42025
P50AA011999Southern California Research Center for ALPD and Cirrhosis42025
UL1TR001863Yale Clinical and Translational Science Award42025
P20GM103449Vermont Biomedical Research Network-Vermont INBRE32025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA016672Cancer Center Support Grant32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant32025

1 to 10 of 1,231Source NIH's project files

See all 1,231 nih grants

Papers2,082

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of Endonuclease G binding protein using a method which specifically isolates binding partners within subcellular compartments.Mol Cell Proteomics202642815854PubTator, text miningPubMed
Pramipexole enhances levodopa's therapeutic efficacy in Parkinson's disease: Role of glutaredoxin-1 (GRX1), peroxiredoxin3 (PRX3), thioredoxin (TRX), 8-hydroxy-2 -deoxyguanosine (8-OHDG), and neurosteroid dehydroepiandrosterone sulfate (DHEA-S).
J Med Biochem202642775310PubTator, text miningPubMed
Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise-Induced Redox Responses in Human Skeletal Muscle.Aging Cell202642625404PubTator, text miningPubMed
Clinical features of four unrelated Japanese patients with autosomal recessive spinocerebellar ataxia type 32.J Hum Genet202642608543PubTator, text miningPubMed
Design, synthesis, and antitumor evaluation of celastrol derivatives targeting PRDX3.Eur J Med Chem202642594679PubTator, text miningPubMed
Up-regulation of peroxiredoxin 3 by high-risk human papillomavirus in cervical cancer cells.Arch Med Sci202642540497PubTator, text miningPubMed
Preclinical characterization and phase 1 clinical testing of targeting mitochondrial peroxiredoxin 3 in cancer.Nat Commun202642448681PubTator, text miningPubMed
Erianin ameliorates liver fibrosis through the PRDX3/NLRX1 axis.Eur J Pharmacol202642392250PubTator, text miningPubMed
Extracellular Vesicles From Young Brain-Mediated Delivery of PRDX3 Ameliorates Alveolar Bone Loss in Periodontitis.J Clin Periodontol202642375016PubTator, text miningPubMed
Identification of Hub Genes, Single-Nucleotide Polymorphisms, and Potential Drug Targets In Breast Cancer Using Transcriptomic Analysis.J Vis Exp202642372043PubTator, text miningPubMed

1 to 10 of 2,082

See all 2,082 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10935

GET https://conductscience.org/api/genes/v1/10935/patents?page=2