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Gene · 10963

STIP1: stress induced phosphoprotein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. STIP1: stress induced phosphoprotein 1. Genes, record 10963. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10963

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Gene

Symbol
STIP1
HGNC
Name
stress induced phosphoprotein 1
HGNC
NCBI Gene ID
10963
NCBI Gene
HGNC ID
HGNC:11387
HGNC
Ensembl
ENSG00000168439
NCBI Gene
Aliases
HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P31948Stress-induced-phosphoprotein 15438Ensembl, GeneID, HGNC

Source UniProt

Patents79

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465656P31948Espacenet
EP 4650780 A22025-11-194389P31948Espacenet
EP 4641201 A22025-10-293928P31948Espacenet
EP 4641202 A22025-10-294806P31948Espacenet
JP 2025517969 A2025-06-123928P31948Espacenet
JP 2025517970 A2025-06-124389P31948Espacenet
JP 2025032204 A2025-03-1136676P31948Espacenet
KR 1020250017231 A2025-02-044806P31948Espacenet
EP 4461818 A22024-11-1336676P31948Espacenet
JP 2024507735 A2024-02-21206P31948Espacenet

1 to 10 of 79

See all 79 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,456

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTIP1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant302025
R01NS059690Molecular Chaperones and Small Molecules172025
ZIABC011032Post-translational modifications of Hsp90142025
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction122025
R01NS073899The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function102025
R01AG067598Chaperome networks in Alzheimer's disease82025
R01AG074004Impact of sex differences on the trajectory of interactome dysfunctions across the AD spectrum72025
P30CA016672Cancer Center Support Grant62025
P50HD103526MIND Institute Intellectual and Developmental Disabilities Research Center52025
R01HL095524Modulation of Lung Disease by Genetic/Epigenetic Profiling52025

1 to 10 of 1,456Source NIH's project files

See all 1,456 nih grants

Papers2,196

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
STIP1 signaling drives protein synthesis in pathological cardiomyocyte hypertrophy.Am J Physiol Cell Physiol202642663117PubTator, text miningPubMed
Structural and energetic landscape of the human HOP-PrPC Axis: Multi-domain stabilization and peptide-mediated disruption by melittin.Biochim Biophys Acta Proteins Proteom202642660210PubTator, text miningPubMed
Correction: Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation.Oncogene202642552450PubTator, text miningPubMed
Proteomics and transcriptomics reveal molecular subtypes and biomarkers of advanced cutaneous T-cell lymphoma.Front Oncol202642528783PubTator, text miningPubMed
Discovery of novel peptidomimetics against HSP90-HOP interactions towards improved cancer therapeutics using machine learning strategies.Front Bioinform202642499390PubTator, text miningPubMed
FKBP8 connects the Hsp70-Hsp90 chaperone machinery to the folding of membrane proteins.Nat Commun202642321214PubTator, text miningPubMed
STIP1/HOP promotes the formation of cytotoxic α-synuclein oligomers.Mol Neurodegener Adv202642291828PubTator, text miningPubMed
Analytical Validation of an ELISA Assay for Maternal Autoantibody-Related Autism.Diagnostics (Basel)202642279533PubTator, text miningPubMed
An Exploratory Study of Heat Shock Protein Changes in Women with Unexplained Infertility.Int J Mol Sci202642278346PubTator, text miningPubMed
Cell type-resolved analysis identifies LOXL2⁺ fibroblasts as key drivers of malignant stromal remodeling in hepatocellular carcinoma.Discov Oncol202642218344PubTator, text miningPubMed

1 to 10 of 2,196

See all 2,196 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10963

GET https://conductscience.org/api/genes/v1/10963/patents?page=2