Gene · 10970
CKAP4: cytoskeleton associated protein 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CKAP4: cytoskeleton associated protein 4. Genes, record 10970. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10970
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q07065 | Cytoskeleton-associated protein 4 | 602 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents57
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 9996 | Q07065 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 565 | Q07065 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 957 | Q07065 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 957 | Q07065 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9996 | Q07065 | Espacenet |
| WO 2025088835 A | 2025-05-01 | 25 | Q07065 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 565 | Q07065 | Espacenet |
| WO 2024218708 A2 | 2024-10-24 | 43 | Q07065 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1184 | Q07065 | Espacenet |
| US 11807679 B2 | 2023-11-07 | 1 | Q07065 | Espacenet |
1 to 10 of 57
See all 57 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,024
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CKAP4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA022453 | CANCER CENTER SUPPORT GRANT | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 3 | 2025 |
| ZICBC011430 | CPTR - Mass Spectrometry Unit | 3 | 2025 |
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 2 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 2 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 2 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 1,024Source NIH's project files
See all 1,024 nih grantsPapers2,190
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A longevity-associated ubiquitin E3 ligase UBE3C governs lamin B1 homeostasis through selective autophagy and delay senescence. | bioRxiv | 2026 | 42620354 | PubTator, text mining | PubMed |
| Exosome-Related Pathogenic Genes in Adenomyosis: A Multi-Omics Mendelian Randomization Study. | OMICS | 2026 | 42610667 | PubTator, text mining | PubMed |
| Senecavirus a 3C protease cleaves RETREG1 to antagonize ER-phagy and promote viral replication via endoplasmic reticulum calcium signaling. | Autophagy | 2026 | 42576627 | PubTator, text mining | PubMed |
| From Bone Marrow Reserve to Metastatic Niche: How Neutrophil-Lineage Cells Shape Skeletal Colonization. | Int J Mol Sci | 2026 | 42450242 | PubTator, text mining | PubMed |
| Plasma proteomics based on machine learning predict the early risk of kidney outcomes in patients with DKD: a prospective cohort study from UK Biobank. | Front Nephrol | 2026 | 42445298 | PubTator, text mining | PubMed |
| Development of high-affinity polyclonal antibodies against chicken CKAP4 and its application in infectious bursal disease. | Int J Biol Macromol | 2026 | 42379451 | PubTator, text mining | PubMed |
| Mendelian Randomization and Single-Cell RNA Sequencing Reveal CKAP4 and PFDN5 as Tumor Cell-Specific Causal Genes for Glioblastoma. | Int J Gen Med | 2026 | 42369563 | PubTator, text mining | PubMed |
| DKK1 activated the NF-κB pathway by binding with CKAP4 to induce PASMC oxidative stress and promote pulmonary arterial hypertension. | Genes Genomics | 2026 | 42329343 | PubTator, text mining | PubMed |
| Lipid droplet-associated gene signatures classify metabolic subtypes and identify PLIN3 as a key driver in hepatocellular carcinoma. | Genes Dis | 2026 | 42327977 | PubTator, text mining | PubMed |
Comprehensive analysis of monocyte palmitoylation-related genes IFITM3 and CCL3-CCR5 axis in crohn's disease progression: Insights from mendelian randomization, multi-omics integration, machine learning, and SHAP methodology. | Comput Biol Chem | 2026 | 42269260 | PubTator, text mining | PubMed |
1 to 10 of 2,190
See all 2,190 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10970
GET https://conductscience.org/api/genes/v1/10970/patents?page=2