Gene · 10979
FERMT2: FERM domain containing kindlin 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FERMT2: FERM domain containing kindlin 2. Genes, record 10979. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10979
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96AC1 | Fermitin family homolog 2 | 680 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46158 | Q96AC1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46160 | Q96AC1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6531 | Q96AC1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6283 | Q96AC1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6283 | Q96AC1 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6531 | Q96AC1 | Espacenet |
| JP 2025062601 A | 2025-04-14 | 11 | Q96AC1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 31622 | Q96AC1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 31624 | Q96AC1 | Espacenet |
| JP 2022092366 A | 2022-06-22 | 722 | Q96AC1 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,173
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FERMT2 papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 36 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 10 | 2025 |
| U24AG056270 | National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS) | 10 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 9 | 2025 |
| U24AG041689 | THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE | 7 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 6 | 2025 |
| P01HL154811 | Cell Adhesion and Signaling in Blood and Vascular Cells | 5 | 2025 |
| R01HL058758 | Molecular basis of ILK-mediated cell adhesion | 5 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 5 | 2025 |
| UL1TR001445 | Clinical and Translational Science Award | 5 | 2025 |
1 to 10 of 1,173Source NIH's project files
See all 1,173 nih grantsPapers1,280
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| DepPrior: integrating CRISPR dependency predictability with multi-omics reproducibility to prioritize candidate LUAD therapeutic targets. | Front Pharmacol | 2026 | 42761694 | PubTator, text mining | PubMed |
| Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approach. | Biochem Pharmacol | 2026 | 42508656 | PubTator, text mining | PubMed |
| ILK binding to β1 integrin is indirect and mediated by kindlin-2. | Proc Natl Acad Sci U S A | 2026 | 42372136 | PubTator, text mining | PubMed |
| Exploring the Toxicological Impact and Mechanisms of DEHP Exposure on Prostate Cancer Through Network Toxicology and Machine Learning Algorithms. | Curr Med Chem | 2026 | 42304923 | PubTator, text mining | PubMed |
| DHT-Induced lncRNA AC092718.4 Promotes Prostate Cancer Cell Proliferation via ceRNA Mechanism. | Genes (Basel) | 2026 | 42194995 | PubTator, text mining | PubMed |
| IFT88/Kindlin-2 Signaling Prevents Mechanical Overloading-Induced PANoptosis of Nucleus Pulposus Cells by Activating FOXP1 SUMOylation. | Int J Biol Sci | 2026 | 42157928 | PubTator, text mining | PubMed |
| The dual role of kindlin-2 in mechanotransduction: A bridge for sensing and a hub for signaling. | Cell Signal | 2026 | 42066827 | PubTator, text mining | PubMed |
| Biophysical membrane responses of hypoxic prostate cancer cells depend on kindlin-2. | Biophys J | 2026 | 42035259 | PubTator, text mining | PubMed |
| Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis. | FASEB J | 2026 | 41996197 | PubTator, text mining | PubMed |
| Kindlins in the cardiovascular system: from development to pathogenesis. | Front Cardiovasc Med | 2026 | 41993866 | PubTator, text mining | PubMed |
1 to 10 of 1,280
See all 1,280 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10979
GET https://conductscience.org/api/genes/v1/10979/patents?page=2