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Gene · 10979

FERMT2: FERM domain containing kindlin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FERMT2: FERM domain containing kindlin 2. Genes, record 10979. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10979

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Gene

Symbol
FERMT2
HGNC
Name
FERM domain containing kindlin 2
HGNC
NCBI Gene ID
10979
NCBI Gene
HGNC ID
HGNC:15767
HGNC
Ensembl
ENSG00000073712
NCBI Gene
Aliases
KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96AC1Fermitin family homolog 26806Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446158Q96AC1Espacenet
JP 2026004568 A2026-01-1446160Q96AC1Espacenet
EP 4650780 A22025-11-196531Q96AC1Espacenet
EP 4641201 A22025-10-296283Q96AC1Espacenet
JP 2025517969 A2025-06-126283Q96AC1Espacenet
JP 2025517970 A2025-06-126531Q96AC1Espacenet
JP 2025062601 A2025-04-1411Q96AC1Espacenet
US 11446398 B22022-09-2031622Q96AC1Espacenet
US 11446398 B22022-09-2031624Q96AC1Espacenet
JP 2022092366 A2022-06-22722Q96AC1Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,173

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFERMT2 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)362025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions102025
U24AG056270National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)102025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study92025
U24AG041689THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE72025
U19AG024904Alzheimer's Disease Neuroimaging Initiative (ADNI4)62025
P01HL154811Cell Adhesion and Signaling in Blood and Vascular Cells52025
R01HL058758Molecular basis of ILK-mediated cell adhesion52025
R01NS017950Precursors of Stroke Incidence and Prognosis52025
UL1TR001445Clinical and Translational Science Award52025

1 to 10 of 1,173Source NIH's project files

See all 1,173 nih grants

Papers1,280

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
DepPrior: integrating CRISPR dependency predictability with multi-omics reproducibility to prioritize candidate LUAD therapeutic targets.Front Pharmacol202642761694PubTator, text miningPubMed
Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approach.Biochem Pharmacol202642508656PubTator, text miningPubMed
ILK binding to β1 integrin is indirect and mediated by kindlin-2.Proc Natl Acad Sci U S A202642372136PubTator, text miningPubMed
Exploring the Toxicological Impact and Mechanisms of DEHP Exposure on Prostate Cancer Through Network Toxicology and Machine Learning Algorithms.Curr Med Chem202642304923PubTator, text miningPubMed
DHT-Induced lncRNA AC092718.4 Promotes Prostate Cancer Cell Proliferation via ceRNA Mechanism.Genes (Basel)202642194995PubTator, text miningPubMed
IFT88/Kindlin-2 Signaling Prevents Mechanical Overloading-Induced PANoptosis of Nucleus Pulposus Cells by Activating FOXP1 SUMOylation.Int J Biol Sci202642157928PubTator, text miningPubMed
The dual role of kindlin-2 in mechanotransduction: A bridge for sensing and a hub for signaling.Cell Signal202642066827PubTator, text miningPubMed
Biophysical membrane responses of hypoxic prostate cancer cells depend on kindlin-2.Biophys J202642035259PubTator, text miningPubMed
Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis.FASEB J202641996197PubTator, text miningPubMed
Kindlins in the cardiovascular system: from development to pathogenesis.Front Cardiovasc Med202641993866PubTator, text miningPubMed

1 to 10 of 1,280

See all 1,280 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10979

GET https://conductscience.org/api/genes/v1/10979/patents?page=2