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Gene · 10984

KCNQ1OT1: KCNQ1 opposite strand/antisense transcript 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KCNQ1OT1: KCNQ1 opposite strand/antisense transcript 1. Genes, record 10984. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10984

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Gene

Symbol
KCNQ1OT1
HGNC
Name
KCNQ1 opposite strand/antisense transcript 1
HGNC
NCBI Gene ID
10984
NCBI Gene
HGNC ID
HGNC:6295
HGNC
Ensembl
ENSG00000269821
NCBI Gene
Aliases
KCNQ1-AS2, KCNQ10T1, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012
NCBI Gene
Type
ncRNA
NCBI Gene

Proteins0

Reviewed human proteins whose Swiss-Prot entry states the gene.

None in this release.

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants907

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKCNQ1OT1 papersNewest fiscal year
P30CA016056Roswell Park Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant32025
R01DK082590Regulation of pancreatic islet cell fate32025
R01GM078455Elucidation of Integrator's Function32025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal32025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement32025
U10CA180899Children's Oncology Group Statistics and Data Center32025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging32025
K08CA255569WT1 as an oncogene and therapeutic target in anaplastic Wilms tumor22025

1 to 10 of 907Source NIH's project files

See all 907 nih grants

Papers2,553

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An lncRNA-aware single-cell framework with donor-level validation identifies reproducible MEG3 enrichment in human liver sinusoidal endothelial cells.Funct Integr Genomics202642758357PubTator, text miningPubMed
Mapping subcellular microenvironments using oligonucleotide-directed proximity labeling.Curr Opin Chem Biol202642612587PubTator, text miningPubMed
LncRNA KCNQ1OT1 promotes hypertrophic scar progression by regulating fibroblast proliferation, migration, and ECM accumulation via the miR-324-5p/SP1 axis.Burns202642612483PubTator, text miningPubMed
Dysregulated lncRNAs are associated with the progressive arterial phenotype in Hutchinson-Gilford Progeria Syndrome.Geroscience202642601545PubTator, text miningPubMed
Expression and mechanistic roles of long non-coding RNAs in diabetic cataract: a systematic review and meta-analysis.Biol Direct202642587300PubTator, text miningPubMed
Beckwith-Wiedemann Syndrome Presenting with Transient Features of Congenital Adrenal Hyperplasia in a Nigerian Neonate.Niger Med J202642544153PubTator, text miningPubMed
A single-cell cell-of-origin audit of the lncRNA RMST: bulk expression under-represents its broad neural expression and over-attributes a liver biomarker.Funct Integr Genomics202642521917PubTator, text miningPubMed
Severe infantile obesity with a maternal GNAS deletion and multi-locus imprinting disturbance including hypomethylation of the KCNQ1OT1:TSS-DMR.Clin Pediatr Endocrinol202642415824PubTator, text miningPubMed
Integrative analysis of circ_DLGAP4, lncRNA KCNQ1OT1, and the miR-9/SOX7 interaction network in chronic kidney disease progression: a case-control study.Funct Integr Genomics202642400831PubTator, text miningPubMed
MicroRNA-597 Suppresses Gastric Cancer Invasion and Progression via RUNX1 Targeting, an Effect Attenuated by the Long Non-Coding RNA KCNQ1OT1.Int J Mol Sci202642353091PubTator, text miningPubMed

1 to 10 of 2,553

See all 2,553 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10984

GET https://conductscience.org/api/genes/v1/10984/grants?page=2