Gene · 10993
SDS: serine dehydratase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SDS: serine dehydratase. Genes, record 10993. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10993
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20132 | L-serine dehydratase/L-threonine deaminase | 328 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63016 | P20132 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1637 | P20132 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1637 | P20132 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 77577 | P20132 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 180548 | P20132 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 10047 | P20132 | Espacenet |
| US 10677795 B2 | 2020-06-09 | 905 | P20132 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 243451 | P20132 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 243451 | P20132 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 243451 | P20132 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants562
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SDS papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| KL2TR002015 | I: Penn State Institutional Career Development Core | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P42ES013661 | Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation | 3 | 2025 |
| UL1TR002014 | Penn State Clinical and Translational Science Institute | 3 | 2025 |
| I01BX005358 | Functional profiling of germline SDH variants associated with cancer susceptibility | 2 | 2025 |
| P30CA006516 | Dana-Farber/Harvard Cancer Center | 2 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 2 | 2025 |
| P30DK048520 | Colorado Nutrition Obesity Research Center | 2 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 2 | 2025 |
1 to 10 of 562Source NIH's project files
See all 562 nih grantsPapers1,988
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Coumarin-Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity. | Chem Biodivers | 2026 | 42814860 | PubTator, text mining | PubMed |
| Synthesis of Siccanin by Computational Subtarget Selection. | J Am Chem Soc | 2026 | 42735144 | PubTator, text mining | PubMed |
Person-Reported and Continuous Glucose Monitoring (CGM) Recorded Hypoglycaemia in People With Insulin-Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo-METRICS Study. | Diabetes Obes Metab | 2026 | 42677701 | PubTator, text mining | PubMed |
| Machine Learning-Based Identification of Survival-Associated CpG Biomarkers in Pancreatic Ductal Adenocarcinoma. | J Precis Med (Amst) | 2026 | 42677177 | PubTator, text mining | PubMed |
| Immunohistochemical Surrogates for Molecularly Defined Renal Tumors. | Diagnostics (Basel) | 2026 | 42651008 | PubTator, text mining | PubMed |
| Metabolomics-based analysis of the effects of different storage temperatures on the post-harvest quality of truffles. | Front Plant Sci | 2026 | 42564050 | PubTator, text mining | PubMed |
| Rewiring Tumor Lifelines: Translating Hypoxia- and Pseudohypoxia-Driven Angiogenesis into Therapeutic Breakthroughs. | Cells | 2026 | 42505404 | PubTator, text mining | PubMed |
| Correction: Deciphering 18F-DOPA uptake in SDH-related head and neck paragangliomas: a radiomics approach. | J Endocrinol Invest | 2026 | 42461578 | PubTator, text mining | PubMed |
| SDH-proficient spindle-cell pediatric gist with peritoneal and umbilical metastatic deposits: A rare case report. | Radiol Case Rep | 2026 | 42437144 | PubTator, text mining | PubMed |
| Pyruvate kinase M2 and Serine Dehydratase are Upregulated in the Macrophages of Human Aortic Atherosclerotic Lesions via Inflammatory Stimuli. | J Atheroscler Thromb | 2026 | 42419938 | PubTator, text mining | PubMed |
1 to 10 of 1,988
See all 1,988 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10993
GET https://conductscience.org/api/genes/v1/10993/patents