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Gene · 10993

SDS: serine dehydratase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SDS: serine dehydratase. Genes, record 10993. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10993

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Gene

Symbol
SDS
HGNC
Name
serine dehydratase
HGNC
NCBI Gene ID
10993
NCBI Gene
HGNC ID
HGNC:10691
HGNC
Ensembl
ENSG00000135094
NCBI Gene
Aliases
SDH, hSDH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20132L-serine dehydratase/L-threonine deaminase3282Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463016P20132Espacenet
EP 4650780 A22025-11-191637P20132Espacenet
JP 2025517970 A2025-06-121637P20132Espacenet
US 11446398 B22022-09-2077577P20132Espacenet
JP 2022524081 A2022-04-27180548P20132Espacenet
US 11078247 B22021-08-0310047P20132Espacenet
US 10677795 B22020-06-09905P20132Espacenet
JP 2019054813 A2019-04-11243451P20132Espacenet
JP 2017121241 A2017-07-13243451P20132Espacenet
JP 2015516143 A2015-06-08243451P20132Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants562

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSDS papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
KL2TR002015I: Penn State Institutional Career Development Core32025
P30CA016672Cancer Center Support Grant32025
P42ES013661Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation32025
UL1TR002014Penn State Clinical and Translational Science Institute32025
I01BX005358Functional profiling of germline SDH variants associated with cancer susceptibility22025
P30CA006516Dana-Farber/Harvard Cancer Center22025
P30CA086862Cancer Center Support Grant22025
P30DK048520Colorado Nutrition Obesity Research Center22025
P30ES005605Environmental Health Sciences Research Center22025

1 to 10 of 562Source NIH's project files

See all 562 nih grants

Papers1,988

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Coumarin-Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity.Chem Biodivers202642814860PubTator, text miningPubMed
Synthesis of Siccanin by Computational Subtarget Selection.J Am Chem Soc202642735144PubTator, text miningPubMed
Person-Reported and Continuous Glucose Monitoring (CGM) Recorded Hypoglycaemia in People With Insulin-Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo-METRICS Study.
Diabetes Obes Metab202642677701PubTator, text miningPubMed
Machine Learning-Based Identification of Survival-Associated CpG Biomarkers in Pancreatic Ductal Adenocarcinoma.J Precis Med (Amst)202642677177PubTator, text miningPubMed
Immunohistochemical Surrogates for Molecularly Defined Renal Tumors.Diagnostics (Basel)202642651008PubTator, text miningPubMed
Metabolomics-based analysis of the effects of different storage temperatures on the post-harvest quality of truffles.Front Plant Sci202642564050PubTator, text miningPubMed
Rewiring Tumor Lifelines: Translating Hypoxia- and Pseudohypoxia-Driven Angiogenesis into Therapeutic Breakthroughs.Cells202642505404PubTator, text miningPubMed
Correction: Deciphering 18F-DOPA uptake in SDH-related head and neck paragangliomas: a radiomics approach.J Endocrinol Invest202642461578PubTator, text miningPubMed
SDH-proficient spindle-cell pediatric gist with peritoneal and umbilical metastatic deposits: A rare case report.Radiol Case Rep202642437144PubTator, text miningPubMed
Pyruvate kinase M2 and Serine Dehydratase are Upregulated in the Macrophages of Human Aortic Atherosclerotic Lesions via Inflammatory Stimuli.J Atheroscler Thromb202642419938PubTator, text miningPubMed

1 to 10 of 1,988

See all 1,988 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10993

GET https://conductscience.org/api/genes/v1/10993/patents