ConductScience.org, home

Library / Genes

SPINK5: serine peptidase inhibitor Kazal type 5

1 protein, 57 patents, 0 drugs, 0 trials, 3,614 NIH grants and 8,491 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSPINK5HGNC
Nameserine peptidase inhibitor Kazal type 5HGNC
NCBI Gene ID11005NCBI Gene
HGNC IDHGNC:15464HGNC
EnsemblENSG00000133710NCBI Gene
AliasesDKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTINCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9NQ38Serine protease inhibitor Kazal-type 51,0646Ensembl, GeneID, HGNCUniProt

Patents 57

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4740954 A22026-05-13103Q9NQ38Espacenet
JP 2026067851 A2026-04-21417Q9NQ38Espacenet
US 12606610 B22026-04-21103Q9NQ38Espacenet
JP 2026048647 A2026-03-179Q9NQ38Espacenet
JP 2026504746 A2026-02-09103Q9NQ38Espacenet
JP 2026004568 A2026-01-1463052Q9NQ38Espacenet
EP 4658758 A12025-12-10103Q9NQ38Espacenet
EP 4650780 A22025-11-191562Q9NQ38Espacenet
EP 4641201 A22025-10-291185Q9NQ38Espacenet
JP 2025147176 A2025-10-0612719Q9NQ38Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3614

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant212,025NIH's project files
U19AI070235Epithelial Genes in Allergic Inflammation202,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease92,025NIH's project files
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis82,025NIH's project files
R01AI125524Kinase Regulation of Nuclear Speckle Function and Splicing during Influenza Virus Infection82,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy82,025NIH's project files
R01GM082946AAV capsids and their cellular interactions72,025NIH's project files

Papers 8491

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814431PubTator, text miningPubMed
42805066PubTator, text miningPubMed
42767772PubTator, text miningPubMed
42748910PubTator, text miningPubMed
42655736PubTator, text miningPubMed
42614128PubTator, text miningPubMed
42612642PubTator, text miningPubMed
42603274PubTator, text miningPubMed
42602184PubTator, text miningPubMed
42573072PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license