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CHAT: choline O-acetyltransferase

1 protein, 9 patents, 0 drugs, 0 trials, 4,425 NIH grants and 11,488 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCHATHGNC
Namecholine O-acetyltransferaseHGNC
NCBI Gene ID1103NCBI Gene
HGNC IDHGNC:1912HGNC
EnsemblENSG00000070748NCBI Gene
AliasesCHOACTASE, CHOACTase, CMS1A, CMS1A2, CMS6NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P28329Choline O-acetyltransferase7488Ensembl, GeneID, HGNCUniProt

Patents 9

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441202P28329Espacenet
EP 4641201 A22025-10-296010P28329Espacenet
JP 2025517969 A2025-06-126010P28329Espacenet
JP 2023519296 A2023-05-1036P28329Espacenet
US 11446398 B22022-09-2014998P28329Espacenet
JP 2022524081 A2022-04-27117969P28329Espacenet
JP 2019054813 A2019-04-11221637P28329Espacenet
JP 2017121241 A2017-07-13221637P28329Espacenet
JP 2015516143 A2015-06-08221637P28329Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4425

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P42ES010356Duke University Superfund Research Center - Developmental Co-Exposures: Mechanisms, Outcomes, and Remediation212,025NIH's project files
P01AG009973Cognition & Hippocampal/Cortical Systems in Aging152,025NIH's project files
R01AA011431FASD Inhibition of ASPH-Notch Mediates Adolescent Cerebral White Matter Pathology-Potential Utility of Non-invasive Extracellular Vesicle Assays102,025NIH's project files
R35GM118182Molecular basis of bioelectronic medicine102,025NIH's project files
P60AA011605Molecular and Circuit Pathogenesis of Alcohol Use Disorders92,025NIH's project files
P30EY003039UAB Core Grant for Vision Research82,025NIH's project files
P30EY004068Core Grant for Vision Research82,025NIH's project files
P51OD011132Emory National Primate Research Center82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30EY001730Vision Research Core72,025NIH's project files

Papers 11488

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822277PubTator, text miningPubMed
42804095PubTator, text miningPubMed
42804018PubTator, text miningPubMed
42802063PubTator, text miningPubMed
42791659PubTator, text miningPubMed
42727580PubTator, text miningPubMed
42727323PubTator, text miningPubMed
42722703PubTator, text miningPubMed
42715617PubTator, text miningPubMed
42706027PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license