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Gene · 11034

DSTN: destrin, actin depolymerizing factor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DSTN: destrin, actin depolymerizing factor. Genes, record 11034. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11034

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Gene

Symbol
DSTN
HGNC
Name
destrin, actin depolymerizing factor
HGNC
NCBI Gene ID
11034
NCBI Gene
HGNC ID
HGNC:15750
HGNC
Ensembl
ENSG00000125868
NCBI Gene
Aliases
ACTDP, ADF, HEL32, bA462D18.2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P60981Destrin1650Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443670P60981Espacenet
EP 4650780 A22025-11-191179P60981Espacenet
EP 4641201 A22025-10-29841P60981Espacenet
JP 2025517969 A2025-06-12841P60981Espacenet
JP 2025517970 A2025-06-121179P60981Espacenet
US 11446398 B22022-09-2024089P60981Espacenet
JP 2022524081 A2022-04-27127060P60981Espacenet
US 11078247 B22021-08-033285P60981Espacenet
WO 2020043864 A12020-03-05678P60981Espacenet
JP 2019054813 A2019-04-11224105P60981Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants973

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDSTN papersNewest fiscal year
R35GM136656Actin filament mechanics and branched network turnover62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant42025
P30CA030199Cancer Center Support Grant (CCSG)42025
R01GM073791Structural-Functional Basis of Actin Cytoskeleton Dynamics42025
P30CA008748Cancer Center Support Grant32025
P40OD010440Caenorhabditis Genetics Center32025
R01GM102262LIM domain kinases: regulation and substrate recognition32025
P20GM103429Partnerships for Biomedical Research in Arkansas22025
P30CA016042Cancer Center Support Grant22025
P30CA016059Massey Cancer Center - Cancer Center Support Grant22025

1 to 10 of 973Source NIH's project files

See all 973 nih grants

Papers1,526

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Unveiling Disulfidptosis and Cuproptosis Vulnerabilities in Pterygium: A Transcriptomic Analysis and In-Silico Drug Repurposing Strategy.Genes (Basel)202642792999PubTator, text miningPubMed
Single-cell transcriptomics combined with Mendelian randomization reveals the pivotal role of WDR83OS in clear cell renal cell carcinoma: An observational and bioinformatic study.Medicine (Baltimore)202642760660PubTator, text miningPubMed
Myosin II-independent contraction of actin filaments in membrane nanotubes.Proc Natl Acad Sci U S A202642709792PubTator, text miningPubMed
Disulfidptosis-related gene DSTN predicts prognosis and promotes malignant progression in head and neck squamous cell carcinoma.Mol Cell Biochem202642101793PubTator, text miningPubMed
Mechanisms of disassembly at the actin filament pointed and barbed ends.Sci Adv202641931606PubTator, text miningPubMed
A multi-strategy framework for enhancing Harris hawks optimization for global optimization problems.Sci Rep202641912695PubTator, text miningPubMed
Programmed cell death: a promising management for Alzheimer's disease.Apoptosis202641904723PubTator, text miningPubMed
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders.Cells202641892327PubTator, text miningPubMed
Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR.Signal Transduct Target Ther202641771837PubTator, text miningPubMed
Identification of disulfidptosis-related genes in immunity and immunotherapy in diabetic foot ulcer.Ann Med Surg (Lond)202641675755PubTator, text miningPubMed

1 to 10 of 1,526

See all 1,526 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11034

GET https://conductscience.org/api/genes/v1/11034/patents?page=2