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RIPK3: receptor interacting serine/threonine kinase 3

1 protein, 36 patents, 0 drugs, 0 trials, 2,288 NIH grants and 5,797 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRIPK3HGNC
Namereceptor interacting serine/threonine kinase 3HGNC
NCBI Gene ID11035NCBI Gene
HGNC IDHGNC:10021HGNC
EnsemblENSG00000129465NCBI Gene
AliasesRIP3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9Y572Receptor-interacting serine/threonine-protein kinase 35189Ensembl, GeneID, HGNCUniProt

Patents 36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461159Q9Y572Espacenet
EP 4650780 A22025-11-19329Q9Y572Espacenet
WO 2025163184 A12025-08-071Q9Y572Espacenet
JP 2025517970 A2025-06-12329Q9Y572Espacenet
KR 1020250067241 A2025-05-154Q9Y572Espacenet
US 12117455 B22024-10-1526Q9Y572Espacenet
JP 2024512669 A2024-03-1931Q9Y572Espacenet
KR 1020230165276 A2023-12-0530Q9Y572Espacenet
US 11446398 B22022-09-2072118Q9Y572Espacenet
US 11332756 B22022-05-1714Q9Y572Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2288

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01AI124346Innate immune signaling and stress response412,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation402,025NIH's project files
R35CA253095Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer272,025NIH's project files
R37AI044828Survival Function of the Fadd-Caspase-8-Flip Complex - MERIT Extension232,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)182,025NIH's project files
R01AI160179Targeting innate immune pathways, and inflammatory cell death in cytokine-mediated diseases182,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase172,025NIH's project files
R35CA231620MECHANISMS OF REGULATED CELL DEATH132,025NIH's project files
R01AI135025Mechanism, Function, and Exploitation of Influenza A Virus-Activated Cell Death102,025NIH's project files
P30CA008748Cancer Center Support Grant92,025NIH's project files

Papers 5797

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822683PubTator, text miningPubMed
42817130PubTator, text miningPubMed
42812611PubTator, text miningPubMed
42808676PubTator, text miningPubMed
42806174PubTator, text miningPubMed
42797864PubTator, text miningPubMed
42796741PubTator, text miningPubMed
42794787PubTator, text miningPubMed
42782792PubTator, text miningPubMed
42781720PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license