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Gene · 1104

RCC1: regulator of chromosome condensation 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RCC1: regulator of chromosome condensation 1. Genes, record 1104. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1104

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Gene

Symbol
RCC1
HGNC
Name
regulator of chromosome condensation 1
HGNC
NCBI Gene ID
1104
NCBI Gene
HGNC ID
HGNC:1913
HGNC
Ensembl
ENSG00000180198
NCBI Gene
Aliases
CHC1, IIAAN, RCC1-I
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P18754Regulator of chromosome condensation42111Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461258P18754Espacenet
JP 2026004568 A2026-01-1461259P18754Espacenet
JP 2026004568 A2026-01-1461260P18754Espacenet
EP 4650780 A22025-11-199380P18754Espacenet
EP 4641202 A22025-10-295602P18754Espacenet
JP 2025517970 A2025-06-129380P18754Espacenet
KR 1020250017231 A2025-02-045602P18754Espacenet
KR 1020230136786 A2023-09-2712P18754Espacenet
US 11446398 B22022-09-2072291P18754Espacenet
US 11446398 B22022-09-2072292P18754Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,038

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRCC1 papersNewest fiscal year
ZIAHD008954Mitotic roles of the Nuclear Transport Machinery112025
R01GM117275Protein N-terminal Methylation Mechanisms and Inhibition92025
P30CA056036Translational Research in Cancer82025
P30CA023168Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant52025
P30CA044579University of Virginia Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P40OD010440Caenorhabditis Genetics Center42025
P30CA010815Consolidated Basic Cancer Research Program32025

1 to 10 of 1,038Source NIH's project files

See all 1,038 nih grants

Papers1,566

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
RCC1 neuropathy mimics childhood axonal Guillain-Barré syndrome with variable clinical severity and survival.Dev Med Child Neurol202642781744PubTator, text miningPubMed
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
Berberine shows potential in mitigating PM2.5-induced breast cancer progression by inducing DNA damage and inhibiting error-prone DNA repair pathways.Apoptosis202642726146PubTator, text miningPubMed
[Role of RCC1-mediated nuclear-cytoplasmic transport process in tumor initiation and progression and its potential clinical value].Sheng Wu Gong Cheng Xue Bao202642343761PubTator, text miningPubMed
Transcriptome-wide association studies implicate RCC1 and PHACTR4 in prostate cancer survival.Eur J Hum Genet202642323493PubTator, text miningPubMed
Insights into retinal disease and non-tubulin glutamylation from a RPGR-TTLL5 complex structure.J Cell Biol202641941273PubTator, text miningPubMed
Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities.J Biomed Sci202641928257PubTator, text miningPubMed
Prolonged Mild Sleep Restriction Changes Epigenome-Wide DNA Methylation in Peripheral Blood Cells: A Randomized Crossover Trial.Aging Dis202641910647PubTator, text miningPubMed
Repurposing mebendazole to reprogram oncogenic and tumor-suppressor networks: Multi-cancer insights from ENOX2, MMP2, RASSF1A, WFDC10A and METTL7A.PLoS One202641886499PubTator, text miningPubMed
Export or explode: Export defects cause micronucleus membrane rupture.J Cell Biol202641874400PubTator, text miningPubMed

1 to 10 of 1,566

See all 1,566 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1104

GET https://conductscience.org/api/genes/v1/1104/patents?page=2